The University of Texas System

University System of Maryland

Broncus Medical Inc.

Broncus

Robert Timmerman

Steve B Jiang

Hak Choy

Arnold Pompos

Henky Wibowo

Amit Ramakant Sawant

Yulong Yan

Arezoo Modiri

Esther Vicente

A method and apparatus for radiation therapy using functional measurements of branching structures. The method includes determining a location of each voxel of a plurality of voxels in a reference frame of a radiation device. The method further includes obtaining measurements that indicate a tissue type at each voxel. The method further includes determining a subset of the voxels based on an anatomical parameter of a respective branching structure of a set of branching structures indicated by the measurements. The method further includes determining a subset of the voxels that enclose an organ-at-risk (OAR) volume. The method further includes determining a value of a utility measure at each voxel. The method further includes determining a series of beam shapes and intensities which minimize a value of an objective function based on a computed dose delivered to each voxel and the utility measure for that voxel summed over all voxels.

System and method for radiation therapy using spatial-functional mapping and dose sensitivity of branching structures and functional sub-volumes

Radiation therapy systems and their components, including secondary radiation shields. At least some versions of the disclosed systems combine a radiation delivery device, a primary radiation shielding device, and a secondary shielding layer into an integrated, modular unit. This is accomplished by using a small direct beam shield capable of blocking a primary beam from a radiation delivery device. In turn, a thinner shielding layer can be used to surround the radiation delivery device and primary shielding device, enabling a single modular unit to be delivered to an installation site. In some embodiments, a bed may be disposed within the secondary shielding layer. In some embodiments, the system is configured to provide up to 4-pi (4&#x3c0;) steradians of radiation coverage to the bed from the radiation delivery device.

Radiation therapy systems that include primary radiation shielding, and modular secondary radiation shields

Growing community of inventors

Westlake, TX, United States of America

Robert Timmerman