University of California

Robert T O'Donnell

Claude F Meares

Larry M Rose

Derick H Lau

Joseph M Tuscano

Yunpeng Ma

The present invention provides compositions comprising the component of fermented wheat germ extract ('FWGE') active in reducing, inhibiting or preventing the proliferation of cancer cells and/or tumors, and methods of making and using such compositions. The active component from FWGE comprises polypeptides having a molecular weight in the range of about 5-100 kiloDaltons (kD), for example, a molecular weight in the range of about 12-50 kD. Exemplary polypeptides from FWGE determined to be active in reducing, inhibiting or preventing the proliferation of cancer cells and/or tumors are listed in Table 1.

Fermented wheat germ proteins (FWGP) for the treatment of cancer

This invention provides novel peptide epitopes recognized by the non-Hodgkin's B cell lymphoma reactive Lym-1 antibody. These novel peptide epitopes are capable of generating antibodies directed against Lym-1 peptide epitope expressing B-NHL cells. This invention is also directed to the treatment of B-NHL.

Antigenic epitopes with Lym-1 reactivity and uses thereof

Antigenic epitopes with LYM-1 reactivity and uses thereof

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Sacramento, CA, United States of America

Robert T O'Donnell