Abiomed, Inc.

Abiomed R & D, Inc.

Abiomed Cardiovascular, Inc.

Avco Everett Research Laboratory, Inc.

Robert T Kung

Meir Rosenberg

Param I Singh

David M Lederman

Robert B Stewart

Fredric L Milder

Timothy E Moutafis

Irving Itzkan

Alan R Millner

Jacob H Barak

Burt D Ochs

Gerard Champsaur

Devices are disclosed for performing transmyocardial revascularization (TMR), percutaneous revascularization and other thermal tissue therapies. The invention utilizes a coring needle with an associated heating element to core out tissue to form a channel in the myocardium, and concurrently thermalize a thin tissue layer at the wall of the channel. The invention yields myocardial channels similar to those obtained with conventional techniques, but with lower energy requirements. The invention further new closure mechanisms for transmyocardial applications.

Coring device for myocardial revascularization

A passive girdle is wrapped around a heart muscle which has dilatation of a ventricle to conform to the size and shape of the heart and to constrain the dilatation during diastole. The girdle is formed of a material and structure that does not expand away from the heart but may, over an extended period of time be decreased in size as dilatation decreases.

Passive girdle for heart ventricle for therapeutic aid to patients

An artificial implantable heart assist system with an artificial myocardium employs a number of flexible, non-distensible tubes with the walls along their long axes connected in series to form a cuff. The tubes are sealed for purposes of inflation and deflation with either hydraulic fluid or pneumatic fluid. The cuff is placed around the natural heart. The inflation of the tubular segments provides that they have a circular cross-section, while in the deflated, or collapsed position without being fluid filled, they are essentially flat sheets. The difference in the perimeter length of the cuff in the plane of the tube short axis, arising from the fact that, inflated, each tube has a length along its perimeter equal to the diameter of the inflated tube, while deflated it has a length equal to the perimeter of the tube divided by two, provides for a contractile force. An energy converter is provided in the system for shuttling fluid between a compliant reservoir and the cuff in phase with the systolic and diastolic phase of the natural heart. This system is powered by an internal implanted battery, which can be recharged transcutaneously from an external power source.

Extra cardiac ventricular assist device

A laser welding apparatus and system for surgically bonding tissue together provides a beam of coherent light at a wavelength corresponding to a specific tissue thickness at which full absorption of the laser energy occurs, and adjusts the energy of the laser beam in response to tissue temperature throughout the tissue thickness to prevent the tissue temperature from either exceeding a predetermined limit or varying outside a predetermined range. Preferably, the coherent light beam has a center wavelength of 1.9 .mu.m, and is variable between 1.85 and 1.91 .mu.m.

Laser welding system

A circulatory apparatus for assisting the movement of fluids with a pulsatile flow. The circulatory apparatus includes a restrictable tube, an element for passively restricting a segment of the tube, two or more elements for selectively restricting segments of the tube, and a controller for directing selective restricting elements. The controller directs restricting elements in a manner that provides a cyclical pulsatile pattern of restriction along the length of the tube.

Tubular circulatory assist device

A multi-wavelength surgical laser apparatus of improved construction employs a fluid-filled stimulated Raman scattering cell in an optical feedback path of a pump laser having a power in a range suitable for surgery, and drives the Raman cell at a high repetition rate in a manner to produce a laser output at a substantially shifted wavelength at a power commensurate with that of the pump laser. In a preferred system, the relative proportions of pump light and Raman scattered light are varied to achieve a desired cutting or coagulating action. Preferably, the pump laser is operated at a pulse repetition rate above five hundred Hz. The fluid Raman medium is pumped across the optical axis of the cell. The flow system effectively doubles the Raman conversion efficiency and permits high power output while lowering the Raman lasing threshold. Systems include a fiber for conducting output light to a surgical probe, and a variable output coupler to vary the relative amounts of pump and Stokes radiation coupled into the fiber. Light generated at visible wavelengths by Stokes processes in the Raman cell provides auxiliary beam for targeting or observation purposes.

Laser surgery system

A vascular connector has a rough surfaced skirt which is trimmed to a size for surgical attachment, and a smooth central tube centrally extending through the skirt to a point upstream of the rough surface. A collar centrally affixed to the skirt releasably engages the tube, which in turn may be fabricated as a permanently attached input conduit of a total artificial heart. For installing the connectors, a skeletal frame fixture secures the central tubes or collars of plural connectors in defined positions corresponding to the attachment ports of the intended pump device.

Surgical cuff

A periodontal probe has a probe finger extending from a handle to an L-shaped distal end which includes a tip adapted for insertion into a periodontal pocket and formed of a thermally insulative material. A temperature sensing element is mounted at the extreme end of the tip. Conductive leads extend from the sensing element, through the probe tip to the handle. In a preferred embodiment, the temperature sensor is a thermocouple or thermistor, and the tip is sealed within an epoxy outer skin. The tip tapers so that the thermal mass of the probe in the vicinity of the sensing element quickly attains the temperature of surrounding tissue while minimally perturbing that temperature. The handle may contain signal processing or temperature display units, and the probe tip preferably includes graduations for indicating probe depth. Interchangeable sensor matching circuit elements adapt sensor elements having different characteristics to a common display driver. A system includes a probe and a processor with a display which indicates periodontal site locations to prompt entry of temperature measurements and to display disease indications based on those measurements. The temperatures are processed and are compared to stored tables of temperature difference distributions, to provide site-specific tissue diagnosis.

Diagnostic temperature probe

An intra-arterial cardiac support system including multiple balloons for placement in the descending aorta with one balloon serving as a pumping balloon and one or more balloons serving as valve balloons, at least one of the valve balloons being positioned distal to the natural heart. The balloons are individually inflated and deflated to provide for sequential pumping action, with the sequence operating in timed relation to the sytstole and diastole of the natural heart.

Intra-arterial cardiac support system

An artificial heart system employing left and right pumping chambers each divided by a membrane into a blood pumping chamber and a hydraulic pumping chamber and a hydraulic pumping system for alternately pumping hydraulic fluid from said left hydraulic chamber toward said right hydraulic chamber and vice versa. A balancing chamber including a flexible membrane placed in the left atrium so that the membrane changes position with changes in the patient's blood pressure, the hydraulic portion of said balancing chamber being fluidically coupled to the right hydraulic pumping chamber in order to allow for a different pumping volume between the left blood pumping chamber and the right blood pumping chamber. A control system employing an algorithm to control the speed of the hydraulic pumping and the direction of flow of the hydraulic pumping in response to sensors sensing the left atrial pressure and the completeness of stroke of the left blood pumping chamber.

Artificial heart

A periodontal probe has a probe finger extending from a handle to an L-shaped distal end which includes a probe stem portion adapted for insertion into a periodontal pocket and formed of a thermally insulative material. A temperature sensing element is mounted at the extreme end of the stem portion. Conductive leads extend from the sensing element, through the probe tip to the handle. In a preferred embodiment, the temperature sensor is a thermistor which, together with the probe stem portion, is sealed within an epoxy outer skin. The tip tapers so that the thermal mass of the probe in the vicinity of the sensing element quickly attains the temperature of surrounding tissue while minimally perturbing that temperature. The handle contains signal processing and temperature display units, and the probe tip includes graduations for indicating probe depth. Interchangeable sensor matching circuit elements adapt sensor elements having different characteristics to a common display driver.

Periodontal probe

A tunable alkali metallic vapor laser system is disclosed. Stimulated Raman scattering (SRS) in a low pressure atomic alkali metallic vapor of potassium or cesium is utilized wherein the atomic vapor is provided and then primed to populate an intermediate level such as the 4P.sub.1/2 level for potassium and the 6P.sub.1/2 level for cesium from which the desired upper laser level is accessible. After the population is created at the intermediate level, it is pumped to a virtual level near the desired upper laser level by a tunable dye laser and, via the SRS process, generates the tunable output laser beam.

Growing community of inventors

Andover, MA, United States of America

Robert T Kung