Minntech Corporation

Ecolab Inc.

Robert T Hall, Ii

Louis C Cosentino

Bradley K Onstad

Robert G Andrus

Randal M Wenthold

Daniel B Carlsen

Rosario M Marino

Paul D Brinda

Richard C Chromecek

Daniel A Baker

Perry L Blackshear, Jr

LeRoy J Fischbach

Jo-Ann B Maltais

Walter B Jansen

Michael C Braun

Daniel T Pigott

Anatol M Hnojewyj

Scott R Vagle

Kimberly L Hall

Robert F Reggin

Terri L Riehm

Daniel J Flesher

Igor P Zdorov

Provided is an anti-microbial composition containing an ester of formic acid, an oxidizer, performic acid and water. Also provided is a premix for making the anti-microbial composition having two parts. One part contains the ester of formic acid and a second part contains the oxidizer. Another method is provided for making the anti-microbial composition in which the ester of formic acid is combined with the oxidizer and water. A further method is provided for sterilizing medical devices, including dialyzer filter modules, wherein the anti-microbial composition is capable of a 1:1 to a 1:12 dilution with water.

Room temperature sterilant for medical devices

An asymmetrical, microporous, hollow fiber membrane is made from a polymeric dope mixture of polysulfone and polyvinyl pyrrolidone dissolved in an aprotic solvent. The physical morphology of the hollow fiber membrane, i.e., the asymmetric microporous wall, is rapidly formed by passing the polymeric dope mixture through an outer annular orifice of a tube-in-orifice spinneret while simultaneously passing a precipitating solution through the central tube of the spinneret. The emerging hollow fiber travels substantially downward for about 0.01-10 m before submersion into a quenching bath. The asymmetrical, microporous, hollow fiber membrane is biocompatible and suitable for use in, for example, dialysis, hemodialysis, ultrafiltration, and water filtration applications.

Hollow fiber membranes and method of manufacture

An asymmetric, microporous hollow fiber membrane comprising a polyimide is disclosed. The hollow fiber membrane is chemically inert to aqueous solutions and/or blood, is immediately rewettable after repeated steam and chemical sterilizations, has superior clearance, sieving, and water permeability characteristics and is usable over a wide range of applications such as dialysis and water filtration. Also disclosed is the process for manufacturing the polyimide hollow fiber membrane.

Provided is an anti-microbial composition containing an ester of formic acid, an oxidizer, performic acid and water. Also provided is a premix for making the anti-microbial composition having two parts. One part contains the ester of formic acid and a second part contains the oxidizer. Another method is provided for making the anti-microbial composition in which the ester of formic acid is combined with the oxidizer and water.

Premix for room temperature sterilant

Room Temperature sterilant

A dialysate filter including asymmetric, microporous, hollow fiber membranes incorporating a polyimide. The dialysate filter connects to the dialysis machine immediately before the dialyzer ensuring complete filtration of the dialysate, easy visual inspection, quick installation and removal, and easy disinfection of the filter.

Dialysate filter including an asymmetric microporous, hollow fiber

Provided is an anti-microbial composition containing an ester of formic acid, an oxidizer, performic acid and water. Also provided is a premix for making the anti-microbial composition having two parts. One part contains the ester of formic acid and a second part contains the oxidizer. Another method is provided for making the anti-microbial composition in which the ester of formic acid is combined with the oxidizer and water. Also provided is a method for sterilizing devices by contacting the surface of the device with the anti-microbial composition containing the ester of formic acid, an oxidizer, performic acid and water.

Method for sterilizing medical devices utilizing a room temperature

Stable, anticorrosive peracetic/peroxide sterilant

A stable, shippable microbicide solution, having improved anticorrosive properties comprising a two part system, the first part consists of a mixture of acetic acid, hydrogen peroxide, peracetic acid, and water. This is referred to for brevity as a peroxide/peracid solution. The second consists of water having dissolved therein a wetting agent which is preferably Victawet.RTM. 35B which is the sodium hydroxide reaction product of an aliphatic alcohol and phosphorous pentoxide. Three other Victawet.RTM. agents have proven operative. Alternatively, Fluorad.TM. FC95, which is a agent of potassium perfluoroalkyl sulfonates may be used. The microbicide may also be a premixed one component system containing the anticorrosive agents of the invention.

Anticorrosive microbicide

An oxidizing sterilant solution comprising percarboxylic acid is disclosed which contains a colorant that is color stable for a useful period in the oxidizing, sanitizing environment.

Sterilant solutions for hollow fiber membranes

Liquid disinfectant compositions are disclosed which can be used to surface-coat substrates with polymeric films which are adherent, water-resistant and which can impart prolonged germicidal properties to the treated surfaces.

Disinfectant polymeric coatings for hard surfaces

A method for non-destructive testing for approximation of oxygen transmission in hollow fiber blood oxygenators or the like is provided which method includes passing a first fluid at a predetermined temperature and volume flow rate through the hollows of the fibers and a second fluid at a second predetermined input temperature and volume flow rate across the outside of the fibers and measuring the heat rise or fall of the fluids and comparing the results with standards for a given blood oxygenator device.

Method of quality control for hollow fiber gas transfer cells

An aqueous acidic solution for cleaning fiberglass without significant discoloration of the surface thereof comprising a water-soluble organophosphonic acid and/or a water soluble acrylic acid polymer, in combination with a higher (alkyl)betaine surfactant and, optionally an amount of alkaline pH modifying substance effective to adjust the pH to a value within the range of about 3.0-7.0. The preferred (alkyl)betaine is lauramidopropyl betaine. Cleaning results are optimized when the acrylic polymer and organophosphate are combined in a cleaning composition having a pH of about 3.5-4.5.

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Welch, MN, United States of America

Robert T Hall, Ii