W. R. Grace Co.

W. R. Grace Co.-conn.

Hampshire Chemical Corp.

Robert S. Holdsworth

Gerald J. O'neill

Robert S Holdsworth

Gerald J O'Neill

Charles W Simons

Charles A Billings

Joel A Gribens

Shawn E Brown

Paul Tarrant

Gerald J O'neill

A hot melt gasket of two superimposed layers. The first layer contains a large amount of tackifier resin to ensure good adhesion to the closure surface. The second layer contains little or no tackifier resin to ensure a good seal between the closure and container. The hot melt gasket is particularly well suited for use on plastic closures, especially polyolefin closures and more especially polypropylene closures.

Method of forming hot melt gaskets

A chlorine-free refrigerant comprised of bis (difluoromethyl)ether; CHF.sub.2 OCHF.sub.2. The refrigerant may be used alone or in combination with other refrigerants. The bis (difluoromethyl) ether refrigerant is environmentally safe, non toxic, non flammable and has the desired physical, chemical and thermodynamic properties necessary for a refrigerant.

Bis (difluoromethyl) ether refrigerant

Hot melt gaskets and method of forming same

A method for removing water from water base can end lining compound after application without the use of a dryer. The method comprises the steps of arranging the lined can ends in a stack, wrapping the stacked can ends in a suitable absorbent material, and allowing the absorbent material to remove the water from the compound by absorption.

Method of removing water from water base can sealant

The following halocyclopropyl halomethyl ethers have been synthesized and found to possess utility as general inhalation anesthetics: 1-chloro-2-chlorofluoromethoxy-1,2,3,3-tetrafluorocyclopropane, 1-chloro-2-difluoromethoxy-1,2,3,3-tetrafluorocyclopropane, 1-bromo-2-chlorofluoromethoxy-1,2,3,3-tetrafluorocyclopropane and 1-bromo-2-difluoromethoxy-1,2,3,3-tetrafluorocyclopropane.

Halocyclopropyl halomethyl ethers

The following chlorocyclopropanes have been found to possess utility as general inhalation anesthetics: 1,1-dichloro-2-methyl-2,3,3-trifluorocyclopropane, 1,2-dichloro-1-fluoro-2-methylcyclopropane, 1,1,2-trichloro-2,3,3-trifluorocyclopropane, 1,1-dichloro-2-trifluoromethyl-2,3,3-trifluorocyclopropane, 1,2-dichloro-1,2,3,3-tetrafluorocyclopropane, 1,1,2,2-tetrachloro-3,3-difluorocyclopropane and 1,1-dichloro-2,3,3-trifluorocyclopropane.

Anesthetic chlorocyclopropanes

Certain new halogenated cyclobutanes have been synthesized and found to possess utility as inhalation anesthetics. They are: 1,4-dichloro-1,2,2-trifluorocyclobutane, 1-chloro-1,2,2,4-tetrafluorocyclobutane, 1,4-dichloro-1,2,2,4-tetrafluorocyclobutane, 1-chloro-1,2,2,3,3-pentafluorocyclobutane, 1,2,2-trifluorocyclobutane, 1-chloro-2,3,3-trifluorocyclobutane, 1-chloro-2,4 4-trifluorocyclobutane, 1-bromo-1,2,2-trifluorocyclobutane, 1-bromo-2-methyl-1,4,4-trifluorocyclobutane and 1-bromo-2-chloro-1,4,4-trifluorocyclobutane.

New halogenated cyclobutanes

The compound 1-chloro-2,2-dimethyl-1,4,4-trifluorocyclobutane has been found to possess useful properties as a general inhalation anesthetic.

1-Chloro-2,2-dimethyl-1,4,4-trifluorocyclobutane as an anesthetics

The following halocyclopropyl halomethyl ethers have been synthesized and found to possess utility as general inhalation anesthetics: 1-chloro-2-chlorofluoromethoxy-1,2,3,3-tetrafluorocyclopropane, 1-chloro-2-difluoromethoxy-1,2,3,3-tetrafluorocyclopropane, 1-bromo-2-chlorofluoromethoxy-1,2,3,3-tetrafluorocyclopropane and 1-bromo-2-difluoromethoxy-1, 2,3,3-tetrafluorocyclopropane.

The following newly synthesized bromofluoromethylcyclopropanes have been found to possess utility as general inhalation anesthetics: 1-bromo-1,2-difluoro-2-methylcyclopropane and 1-bromo-1-fluoro-2-methylcyclopropane.

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Arlington, MA, United States of America

Robert S Holdsworth