Wisconsin Alumni Research Foundation

Robert Ricardo Meyer

Warren D D'Souza

Michael Charles Ferris

Athula De Alwis Gunawardena

Leyuan Shi

A system and method for producing an intensity modulated arc therapy ('IMAT') treatment plan are provided. A plurality of segmentations are generated, from which the IMAT treatment plan is determined. Apertures within each segmentation are ordered by minimizing the total leaf movement between pairs of segmentations in adjacent angles, during which corresponding minimum total leaf movement values between such pairs are calculated. From these segmentations, a network model is used to select those segmentations to be used in the IMAT treatment plan. The apertures in the selected segmentations are then modified by minimizing total leaf movement relative to the selected segmentations, and subject to physical constraints such as a maximum leaf movement constraint or interdigitation constraint. Segmentation errors in the modified segmentations are then locally minimized using a network model and a row-non-convexity measure to determine the order in which apertures are to be optimized.

System and method for intensity modulated arc therapy treatment planning

A novel approach to generating radiation treatment plans through a nested partitions framework provides an optimization of radiation delivery. The nested partitions approach couples beam angle selection and dose optimization to solve treatment planning problems. An optimal beam angle selection is provided to best treat tumors, while minimizing exposure to the surrounding healthy tissues.

Growing community of inventors

Madison, WI, United States of America

Robert Ricardo Meyer