University of Washington

Robert Reife

Keith L Knutson

Richard P Darveau

A preparation containing lipopolysaccharide (LPS) ofhaving a molecular negative mass ion of 1435 or 1449 is used as an immune system modulator to redirect a host's immune system against an antigen of interest. The 1435/1449 LPS preparation can be isolated fromor prepared as a derivative or mimetic thereof. The immunomodulating preparations of1435/1449 can be used as a vaccine adjuvant, and can be used to stimulate an immune response against a selected antigen associated with a disease of interest, such an antigen associated with a tumor, infectious disease, autoimmune disease, MHC antigen, or to modulate asthma or other inflammatory conditions.

Growing community of inventors

Redmond, WA, United States of America

Robert Reife