Alza Corporation

Robert R Skluzacek

David E Edgren

Gurdish K Bhatti

Shu W Li

Brian L Barclay

Patrick S-l Wong

Patrick S L Wong

Patrick SL Wong

A membrane system comprising an interior wall, a fluid-permeable exterior wall surrounding the interior wall and an internal compartment defined by the membrane system, wherein fluid permeability of the interior wall is responsive to osmolarity of an osmotic core within the internal compartment are disclosed. A controlled release dosage form comprising the membrane system and a process for delivering an osmotically active formulation from an osmotic pump over an extended period of time are also disclosed.

Extended release dosage form

A dosage form is disclosed comprising means for delivering essentially a total dose of drug.

Dosage form comprising means for changing drug delivery shape

A dosage form comprising a composition comprising a drug surrounded by an interior and an exterior wall with an exit for administering the drug to a patient; and a method of using the dosage form are disclosed for an indicated therapy.

A dosage form comprising a composition comprising a drug surrounded by a first coat and a second coat with an exit for administering the drug to a patient; and a method of using the dosage form are disclosed for an indicated therapy.

Dosage form having first and second coats

A dosage form is disclosed comprising a wall that surrounds a bilayer core with exit passageway for communicating with the bilayer core in the wall.

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Newark, CA, United States of America

Robert R Skluzacek