Institute for Environmental Health, Inc.

Sample6 Technologies, Inc.

Phage Diagnostics, Inc.

Robert Patrick Shivers

Michael Sandor Koeris

Jayson Linn Bowers

Daniel Robert Brownell

Jason Wyatt Holder

Edyta Krzymanska-Olejnik

Michael Cappillino

Timothy Kuan Ta Lu

Julie Thomason

Methods of detecting target bacteria are provided. In some embodiments, the methods comprise exposing a sample to a phage capable of infecting target bacteria, said phage comprising a heterologous nucleic acid sequence encoding a marker. In some embodiments, the target bacteria comprise. In some embodiments, the target bacteria are all. Recombinantphage comprising a heterologous nucleic acid sequence encoding a marker are also provided as are useful combinations of such phage and articles of manufacture comprising such phage, among other things.

Recombinant phage for listeria detection

Composition and methods for the detection of one or more target microbe(s) are provided. Compositions of the disclosure include at least one recombinant phage capable of infecting a target microbe, said phage comprising at least a capsid protein sequence, a ribosome binding site, and a codon-optimized marker. Compositions of the disclosure may further include an aqueous solution that enhances the ability to detect marker expression upon phage infection of the target microbe. In some embodiments the target microbe include is

Codon optimized recombinant phage and methods of using same

Methods of detecting target bacteria are provided. In some embodiments the methods comprise exposing the sample to a phage capable of infecting a set of target bacteria and comprising a heterologous nucleic acid sequence encoding a marker. In some embodiments the target bacteria comprise. In some embodiments the target bacteria are all. Recombinantphage comprising a heterologous nucleic acid sequence encoding a marker are also provided as are useful combinations of such phage and articles of manufacture comprising such phage, among other things.

Phage-based bacterial detection assay

Methods of making recombinant phage, compositions and articles of manufacture of same for bacterial detection

Growing community of inventors

Watertown, MA, United States of America

Robert Patrick Shivers