Catheter Precision, Inc.

Boston Scientific Scimed, Inc.

St Jude Medical, Atrial Fibrillation Division, Inc

Peacs Investments B.v.

Robert Pacheco

Steve Foley

David C Jenkins

Eugene J Jung

Reinhard J Warnking

Hiroshi Nakagawa

Brandon D Guarino

Troy Terrance Tegg

Saurav Paul

Thomas Bates Jackson

Barry Mitchell Yomtov

Daniel Leonard Fuller

Charles Bryan Byrd

James D Savage

Dong Ik Shin

Jaime Merino

Yitzhak I Shai

Eric Scott Vaughan

James Holte

Mick Kuehn

Matt Pasvogel

Luke Hares

Various embodiments include methods of cardiac resynchronization therapy (CRT). Various embodiments may include: generating, using a processing unit, a cardiac activation map including a three-dimensional (3D) heart model of the heart that shows coronary vessels of a patient and shows the propagation of electrical signals through the 3D heart model; determining the location of a left bundle branch block (LBBB) based on the cardiac activation map; implanting a first pacing device and a second pacing device into the patient; stimulating the His Bundle of the heart using the first pacing device; and stimulating the left ventricle (LV) of the heart at a position downstream of the LBBB with respect to a direction of electrical conduction through the LV using the second pacing device after stimulating the His bundle.

Method of cardiac resynchronization therapy

Various embodiments include a catheter positioning device that may include a sled member, a sled base, an active damping system, a sensor, and a control system. The sled member may be configured to accept a handle of a catheter. The sled base may be configured to move the sled member along a length of the sled base for positioning the catheter within a patient. The active damping system may be configured to apply a force to the sled base to resist movement of the sled base in response to a control signal. The sensor may be configured to generate signals in response to a movement of the sled base. The control system may be configured to receive sensor signals from the sensor and transmit control signals to cause the active damping system to apply the force to resist movement of the sled base indicated in the received sensor signals.

Components and methods for balancing a catheter controller system with a counterweight

Various embodiments enable an introducer for a catheter to be rotated around an axis and/or traversed backward and/or forward along the axis. In various embodiments, positioning of an introducer may be enabled by an introducer support configured to be rotated around an axis and/or extended or retracted along the axis. The introducer may be manually operated and/or operated by motors in a nose cone of a catheter positioning system. In various embodiments, a portion of the introducer support may be configured to flex. In other embodiment, positioning of an introducer may be enabled by an adjustable nose cone of a catheter positioning system.

Introducer support for a catheter positioning system

Various embodiments include methods for conducting cardiac resynchronization therapy and systems implementing the method. Various embodiments may include generating, using a processing unit, a three-dimensional (3D) activation map showing the propagation of electrical signals through a heart of a patient, identifying a stimulation point on the heart for cardiac resynchronization; generating real-time images of the heart, displaying, on a display unit, the stimulation point on the real-time images as a virtual stimulation point, implanting a pacing device into the patient at the identified stimulation point, such that the pace maker is aligned with the virtual stimulation point in the real-time images, and stimulating the heart using the pacing device.

System and method for cardiac resynchronization

Adjustable nose cone for a catheter positioning system

Various embodiments provide a catheter positioning device with components for controlling actuators of the catheter in multiple axes. A catheter may be attached to a sled member by a modular plate with one or more actuator interfaces that may couple with the actuators of a catheter handle. One or more motors or drives in the sled member may move the actuator interfaces of the modular plate to control one or more actuators on the catheter in different axes. In various embodiments the sled member may have a clam shell design in which two or more sides of the sled member close around the catheter handle. In further embodiments, the sled member may include adjustable faces that can fit different types of modular plates and thereby control actuators on different types of the catheter.

Components for multiple axis control of a catheter in a catheter positioning system

Methods, devices, and systems for predicting, diagnosing, and preventing adverse events during an ablation procedure are described. A method for providing ablation energy includes receiving a first signal based on biological activity of a tissue of a patient. The method further includes analyzing the first signal to yield a first data set, establishing a threshold parameter according to the first data set, and providing ablation energy for the ablation of a biological site.

Electrogram-based ablation control

Systems, methods, and devices of the various embodiments provide a hoop drive assembly. A hoop drive assembly according to the various embodiments may include one or more toothed rings and one or more motors coupled to the one or more toothed rings. In the various embodiments, rotation of the one or more toothed rings may change an orientation of a turret supported by the hoop drive assembly and/or move a control actuator of a catheter held in a modular plate coupled to the turret.

Remote catheter positioning system with hoop drive assembly

Systems, methods, and devices of the various embodiments provide a remote controller for a catheter positioning system configured to be operated with a single hand by a catheter positioning system operator. In an embodiment, the remote controller may include a thumb joystick control, first wheel control, and second wheel control. In an embodiment, the remote controller may include various visual indicators and/or haptic feedback mechanisms providing information to a catheter positioning system operator.

Single hand operated remote controller for remote catheter positioning system

Various embodiments provide systems and methods for controlling a catheter with a catheter positioning device by using a remote controller. As the catheter is advanced by the catheter positioning device, a counterweight may be adjusted to balance the catheter positioning system. In further embodiments, the counterweight may be configured to move to balance a sled member such that any total moment exerted on a sled base remains constant. In further embodiments, the counterweight may be controlled by a control system based on one or more sensors coupled with the catheter positioning system.

Embodiments include a spreader and a resealable delivery channel in a catheter positioning system configured to introduce a catheter into the resealable delivery channel. The spreader may have shapes configured to help users insert the spreader and a catheter into the resealable delivery channel and to retain the spreader and the catheter within the resealable delivery channel. The resealable delivery channel may be shaped to accommodate the spreader or catheter. The resealable delivery channel may include flexible plastic lips that are moveable to facilitate insertion of the spreader and a catheter into the resealable delivery channel.

Components and methods for a catheter positioning system with a spreader and track

A cardiac ablation device, including a steerable catheter () and an expandable ablation element () incorporating one or more balloons () at the distal end of the catheter, has a continuous passageway () extending through it from the proximal end of the catheter to the distal side of the expandable ablation element. A probe () carrying electrodes is introduced through this passageway and deploys, under the influence of its own resilience, to a structure incorporating a loop () which is automatically aligned with the axis of the expandable ablation device, so that minimal manipulation is required to place the sensor probe.

Ablation devices with sensors structures

Various embodiments provide systems and methods for controlling a catheter with a catheter positioning device by using a remote controller and a guidewire control mechanism that may be used to draw a guidewire through a catheter coupled with the catheter positioning system. As the catheter is advanced over the guidewire by the catheter positioning device, the guidewire control mechanism may draw the guidewire away, such as collecting any slack on the guidewire. In further embodiments, the guidewire control mechanism may match the speed at which the guidewire is drawn to the speed at which the catheter advances and thereby maintain the position of the guidewire relative to the patient.

Growing community of inventors

Bayside, NY, United States of America

Robert Pacheco