Schwarz Pharma Ag

Lts Lohmann Therapie-systeme Ag

Lts Lohmann Therapie-systeme Gmbh + Co. Kg

Lts Lohmann Therapie-systemme Gmbh & Co. Kg

Robert P Klein

Reinhold Meconi

Hans-Rainer Hoffmann

Hans-Michael Wolff

Walter Müller

Dieter Beutner

Rainer Hoffmann

Gunter Cordes

Hans M Wolff

Henning Von Knobelsdorff

A transdermal therapeutic system in plaster form for controlled release of oestradiol in combination with norethisterone acetate, comprising a backing layer, a reservoir supersaturated with active ingredients which is attached to said backing layer and prepared using polyacrylate pressure-sensitive adhesives and crystallization inhibitors, and a detachable protective layer, is characterized in that the crystallization inhibitor is an amino-containing polymer.

Transdermal therapeutic system containing hormones and crystallization inhibitors

Nitroglycerine plaster and process for its production

The present invention relates to active substance plasters for the controlled release of active substances to the skin consisting of a backing layer, an adhesive film connected therewith which film is water-soluble and consists of pressure-sensitive adhesive which comprises water-swellable polymers and in which the active substance is at least partially soluble, and of a removable protective layer covering the adhesive film, in which plasters the pressure-sensitive adhesive is based on homo and/or copolymers with at least one derivative of the acrylic or methacrylic acid, and which comprise as active substances, partially or completely dissolved in the adhesive, at a concentration of 0.5 to 10.0%-wt estrogens and their pharmaceutically acceptable derivatives alone or in combination with gestagens.

Estrogen-containing active substance plaster

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Neuwied, Germany

Robert P Klein