Codexis, Inc.

Novozymes A/s

Other

Microbiogen Pty. Ltd.

University of Florida Research Foundation, Incorporated

University of Rochester

Robert Osborne

Xiyun Zhang

Jeffrey C Moore

Vesna Mitchell

Erika M Milczek

Khin Yu Naing Htwe

Jonathan Vroom

Jovana Nazor

Jack S Liang

Rama Voladri

Birgit Kosjek

David Entwistle

Ravi David Garcia

Shane Grosser

Matthew Truppo

Gjalt W Huisman

Paul Vincent Harris

Fernando Valle

Tomoko Matsui

Shiro Fukuyama

Michael Glenn Catlett

Monica Tassone

Charles A Thornton

Thurman Wheeler

Ryoko Kataoka

Jed Lee Hubbs

Krzysztof Sobczak

Jill Miller

Louis Clark

Paul Victor Attfield

Smita Shankar

Xin Li

Catherine M Cho

Philip John Livingstone Bell

Yihui Zhu

Monica Bhatia

Hamid Rismani Yazdi

Alan Jay House

Patricia Choudhary

U Loi Lao

Saul Nitsche Rocha

Khin Yu Htwe

Maurice S Swanson

Described herein are recombinant fermenting organisms having a heterologous polynucleotide encoding an alpha-amylase and/or a heterologous polynucleotide encoding a trehalase. Also described are processes for producing a fermentation product, such as ethanol, from starch or cellulosic-containing material with the recombinant fermenting organisms.

Yeast expressing a heterologous trehalase for ethanol production

The present invention provides improved P450-BM3 variants with improved activity. In some embodiments, the P450-BM3 variants exhibit improved activity over a wide range of substrates.

P450-BM3 variants with improved activity

The present invention provides engineered proline hydroxylase polypeptides for the production of hydroxylated compounds, polynucleotides encoding the engineered proline hydroxylases, host cells capable of expressing the engineered proline hydroxylases, and methods of using the engineered proline hydroxylases to prepare compounds useful in the production of active pharmaceutical agents.

Engineered proline hydroxylase biocatalysts for hydroxylation of chemical compounds

Yeast expressing a heterologous alpha-amylase for ethanol production

Vectors for expression of biocatalysts

Described herein arestrains MBG5038 and MBG5012 deposited under the Budapest Treaty and having accession Nos. NRRL Y67549 and NRRL Y67700, respectively, or a derivatives of strains NRRL Y67549 or Y67700 which exhibit one or more properties or defining characteristics ofstrains MBG5038 or MBG5012. Also described are compositions comprising theyeast and naturally occurring and/or non-naturally occurring components, as well as are processes for producing ethanol from starch-containing material using the strains.

Yeast for ethanol production

Polynucleotides encoding biocatalysts and methods for hydroxylation of chemical compounds

The present invention provides kinase inhibitor analogs with improved properties, such as improved efficacy, pharmacokinetics, safety, and specificity. In some embodiments, the present invention provides lapatinib analogs that provide therapeutic benefits.

N-substituted 4-aminoquinazoline derivatives and methods of use

Growing community of inventors

Raleigh, NC, United States of America

Robert Osborne