Other

Cambridge Neuroscience, Inc.

Robert N McBurney

Stanley M Goldin

Mark Andrew Marchionni

Nagesh K Mahanthappa

David I Gwynne

Olivia Bermingham-McDonogh

Methods are provided for treatment of eye disorders and injury, including methods for treatment of reduced flow of blood or other nutrients to retinal tissue and/or optic nerve, methods for treatment of retinal ischemia and trauma and methods for treatment for optic nerve injury/damage.

Methods of treatment of eye trauma and disorders

The present invention relates to methods of affecting cellular communication in a vertebrate. The communication is affected by the administration of a neuregulin to a vertebrate, where the neuregulin interacts with a first cell type which results in the production of a product (i.e., Product A). This product, in turn, affects the function of a second cell type. Methods are disclosed in which the affect in function of the second cell type, described above, results in the production of a second product (i.e., Product B) which, in turn, can affect the function of the first cell type or a third cell type. Additional methods are included for treatment of disorders involving an altered or inadequate level of production of a product involved in cellular communication.

Use of neuregulins as modulators of cellular communication

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Newton, MA, United States of America

Robert N McBurney