Angio-medical Corp.

Boston University

Robert McCluer

Nicholas Catsimpoolas

Robert S Sinn

James Evans

Ahmad R Kamarei

Michael I Klibaner

Ann L Griffith

Takashi Mise

Lipid material or ganglioside from mammalian sources e.g. bovine and porcine brain or omentum is used to treat peptic ulcers.

Method for the treatment of gastric ulcer

A method for causing or increasing angiogenesis is described. The method involves administering to a subject, such as a human being in need of angiogenesis an angiogenically effective amount of an angiogenically effective, pharmaceutically acceptable oligosaccharide or mixture of oligosaccharides.

Method for provoking angiogenesis by administration of angiogenically

Compositions which contain lipid containing molecules possessing angiogenic activity are disclosed. The lipid containing molecules have been found in mammalian tissue, particularly the omentum, of various animals. Additionally, known lipids, such as gangliosides, are unexpectedly found to possess angiogenic activity. A method for obtaining the omentum-derived lipids, and for use of these and known lipids, are disclosed as well.

Method for enhancing angiogenesis with lipid containing molecules

Lipid containing molecules and compositions, including gangliosides and omental tissue extracts had previously been found to be effective in increasing angiogenesis. It has now been found that these same materials cause increased localized perfusion in mammals. A method for providing increased perfusion, using these compositions, is presented herein.

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Acton, MA, United States of America

Robert McCluer