Nupulse, Inc.

L-vad Technology, Inc.

Nupulsecv, Inc.

North Carolina State University

Safetyminded Holdings, Inc.

Robert M Smith

Valluvan Jeevanandam

Roger William Snyder

Paul G DeDecker

Adrian Kantrowitz

Allen B Kantrowitz

Douglas Edward Ivers

Paul S Freed

Shamim Samadi

Ryan Daniel McCormick

Sai Bhargav Dasari

Nagarjuna Reddy Chinta

Cranos M Williams

Divyakumar Mahiman Badheka

Hubert Troy Nagle, Jr

Terrance J Ransbury

Kenneth C Armstrong

Darrel Eugene Self

Charles Mack Gouge

Brian Howard Novack

Adrian Kantrowski

Duane Pinto

Guruprasad Anapathur Giridharan

Douglas Altschuler

Joshua Ryan Woolley

The present disclosure is directed towards systems and methods built for predictively timing the inflation and/or deflation of an intra-aortic balloon pump. A controller operates in three states: (1) initialization state, (2) learning state, and (3) peak detection state. The controller decomposes a patient's electrocardiogram signal to a power signal. It then learns characteristics of the patient's electrocardiogram signal during the learning state and computes adaptive threshold parameter values. During the peak detection state, the controller applies the learnt threshold parameter values on a current electrocardiogram signal to identify occurrence and timings of R peaks in the electrocardiogram signal. The R-to-R peak timings are then used to trigger inflation of an intra-aortic balloon pump.

Predictive QRS detection and R-to-R timing systems and methods

Intravascularly delivered blood pumps and associated devices, systems, and methods, are disclosed herein. A system for intravascularly implanting a blood pump in accordance with embodiments of the present technology can include, for example, an elongated delivery dilator having a first end portion, a second end portion, and a lumen extending between the first end portion and the second end portion. The elongated delivery dilator is configured to advance over a guidewire positioned within the patient's vasculature and to extend through the patient's vasculature between a first blood vessel and a second blood vessel. A pump assembly includes an expandable member and a driveline. The expandable member is configured to be positioned in a patient's descending aorta to provide circulatory support to the patient's heart.

Intravascularly delivered blood pumps and associated devices, systems, and methods

The invention provides a blood pump for use with an intravascular ventricular assist system (iVAS), as well as a method for utilizing the blood pump to treat heart failure.

Blood pump assembly and method of use thereof

The invention provides an introducer assembly for delivering a blood pump into vasculature of a subject, as well as a method for utilizing the assembly.

Introducer assembly and method of use thereof

An implantable aortic blood pump includes a rigid body having wall extending along a long axis and defining an inflation port portion with an inflation aperture therethrough. The aperture is fluid communication with an inner surface of the body and on a fluid supply, the body is preferably independent of an external brace or an external stiffener, yet still has a cantilevered deformation of less than 8 millimeters in response to a 200 gram weight suspended from a front body edge. A deflecting structure of a membrane deflects in response to fluid pressure so as to pump blood when the pump is secured to a subject aorta.

Rigid body aortic blood pump implant

A skin interface device ('SID') for a cardiac assist device, including a SID cap having a first housing, an annular sleeve, and a first annular winding disposed over said annular sleeve. The SID further includes a SID base having a second housing formed to include a tubular portion, a cylindrical member disposed in said tubular portion, and a second annular winding disposed around said cylindrical member. The SID cap is configured to be rotationally attached to said SID base. When the SID cap is attached to the SID base, the second annular winding is disposed within the first annular winding, and the relative positions of the first annular winding and the second annular winding are fixed both laterally and vertically.

Skin interface device for cardiac assist device

An aortic blood pump is described that is secured to a patient aorta that can be inflated and deflated in response to selective communication with a source of pressurized fluid or air. An expanded stent creates an area in with the pump and inflate and deflate. A system is also detailed including the pump and an external air line external to a patient body.

Stable aortic blood pump implant

A human safety system includes a circuit including a microcontroller and at least one power source; a probe in communication with the circuit; at least one use detector in communication with the circuit; and at least one alert indicator in communication with the circuit. A method of using a human safety device, the method includes initiating operation of the human safety device; arranging the human safety device in communication with skin; and monitoring the human safety device for alert indicators. A method of monitoring a user includes waking from sleep state; sensing at least one condition of the user; determining if the sensed condition is in a human condition; continuously monitoring the condition of the user; and, returning to sleep state when the user condition is outside of the human condition for an amount of time.

Human safety indicator

Devices and methods are disclosed for implanting, positioning, removing, replacing and operating intra-aortic balloon pumps.

Intra-aortic balloon pump assembly for ventricular assist device

Internal drive line for ventricular assist device

An aortic blood pump is described that can be inflated and deflated in response to selective communication with a source of pressurized fluid or air. The pump includes a structure adapted to maintain implant stability in the face of mechanical and fluid forces to which it is exposed in situ. The pump may include a wall adapted to maintain implant stability by connection of the wall to a stiffening element, such as a stent, a brace, a stiffener or any combination of these. Additionally, the pump optionally includes a wall adapted to maintain implant stability by configuring the interior volume to generally follow the contour of the native human aorta.

Growing community of inventors

Raleigh, NC, United States of America

Robert M Smith