University of Illinois

Philadelphia Health and Education Corporation

Robert M Moriarty

Jerome W Kosmeder, Ii

Timothy Michael Block

John M Pezzuto

Richard C Moon

Baohua Gu

Mahendra N Deshpande

Rajendra C Shah

Lynda Li Song

An anti-viral compounds effective against viruses belonging to the Flaviviridae family, wherein the anti-viral compounds are 1,5-dideoxy-1,5-imino-D-glucitol derivative compounds having the general formula (I) wherein R, R, Rand Rare the same or different and are selected from the group consisting of hydrogen, acyl, benzyl, alkyl, aryl, sulfonyl, phosphonyl, silyl, Ris at least one of alkyl or branched alkyl, heteroalkyl or aryl, R' is a bridging group selected from at least one of bicycle[2.2.1]heptyl, bicycle[3.2.1]octyl, oxa analogs, admonyl and cubyl, n&#x2032;=2-10, n&#x2033;=1-10, enantiomers and stereoisomers of said compounds and physiologically acceptable salts or solvates of said compounds, enantiomer or stereoisomer.

Iminosugar compounds with antiflavirus activity

A composition and method of cancer chemoprevention is disclosed. The composition and method utilize 4'-bromoflavone as a cancer chemo-preventative agent in mammals, including humans.

Use of 4'-bromoflavone in a cancer chemopreventative composition and

Growing community of inventors

Michigan City, IN, United States of America

Robert M Moriarty