Medtronic, Inc.

Other

Robert Leinders

Arnoldus P Bakels

Nathan Andrew Torgerson

Koen J Weijand

Cobus De Roos

Todd P Goblish

Todd D Heathershaw

John Delfin Rodriguez

Marc T Stein

Gary William King

Michael D Baudino

John W Forsberg

John J Grevious

Pierre Andre Grandjean

Raymond F McMullen

Steven L Jensen

Greg Hrdlicka

Mark T Stein

Craig L Schmidt

Alain F Carpentier

David E Francischelli

Mark A Christopherson

Paulus Cornelis Van Venrooij

Richard P M Houben

Adrianus P Donders

Ivan M Bourgeois

Paul M Skarstad

Nicolaas M Lokhoff

Antoine N Camps

Markus Haller

Kendra K Gealow

Martinus A G M Bakx

Jon Werder

Pierre G Wielders

Curtis D Deno

Marty Bakx

Richard PM Houben

Apparatus and method provide flexibility in generating a stimulation waveform to an electrode of an implantable medical device. The stimulation waveform comprises at least one stimulation pulse. The embodiment of the invention supports a generation of a stimulation pulse in which an amplitude and an electrical polarity of the stimulation pulse can be dynamically changed. The embodiment comprises a capacitor arrangement, a regulator and a switching array. The capacitor arrangement can be reconfigured with respect to an electrical reference through the switching array in order for the regulator to deliver the stimulation pulse to a pair of electrodes. In another embodiment, a plurality of stimulation waveforms are generated in which different stimulation waveforms are associated with different electrodes. With the embodiment, a plurality of regulators are connected and reconfigured to the capacitor arrangement in order that the different stimulation waveforms are generated by different regulators.

Voltage/current regulator improvements for an implantable medical device

The locus of electrically excitable tissue where action potentials are induced can be controlled using the physiological principle of electrotonus. In one embodiment, first and second pulses are applied to first and second electrodes, respectively, to generate first and second subthreshold potential areas, respectively, within the tissue. The locus within the tissue where action potentials are induced is determined by a superposition of the first and second subthreshold areas according to the physiological principle of electrotonus. In another embodiment, a two-dimensional array of electrodes are formed. The cathode may be positioned near the center of the two-dimensional array or may be left out. The first and second subthreshold areas may thereby be steered. An array of anodal rings may be used to contain the field of excitation.

Technique for adjusting the locus of excitation of electrically excitable tissue

Apparatus and method for independently delivering a plurality of therapy programs in an implantable medical device. A therapy controller configures the device to generate independent pulse trains associated with a plurality of therapy programs and dynamically configures the electrodes to deliver the independent pulse trains to the patient. Once configured, the implantable medical device delivers the plurality of therapy programs to the patient wherein the therapy programs may overlap in time.

Independent therapy programs in an implantable medical device

Apparatus and method provide flexibility in generating a stimulation waveform to an electrode of an Implantable Neuro Stimulator (INS). The stimulation waveform is synthesized for each rate period interval. Each rate period interval is partitioned into time intervals, during which stimulation pulses, recharging, and time duration delays may be induced. With the embodiment of the invention, a second stimulation pulse, having different electrical characteristics than a first stimulation pulse, may be generated during the rate period interval. An embodiment utilizes apparatus comprising a waveform controller and a waveform generator that are controlled by the waveform controller. The waveform controller uses waveform parameters to instruct the waveform generator to form stimulation pulses. Any of the components may be adjusted or deleted in the generation of the stimulation waveform. The embodiment enables any of the associated waveform parameters to be updated at the waveform controller in order to alter the stimulation waveform.

Programmable waveform pulses for an implantable medical device

In general, the invention is directed to an IMD having a piezoelectric transformer to power a lead-based sensor. The IMD powers the piezoelectric transformer with a low amplitude signal. The piezoelectric transformer serves to convert the voltage level of the low amplitude signal to a higher voltage level to drive the sensor produced by a battery in the IMD to voltage levels appropriate for IMD operation. A piezoelectric transformer offers small size and low profile, as well as operational efficiency, and permits the IMD to transmit a low amplitude signal to a remote sensor deployed within an implantable lead. In addition, the piezoelectric transformer provides electrical isolation that reduces electromagnetic interference among different sensors.

Implantable lead-based sensor powered by piezoelectric transformer

An implantable medical device includes a control circuit for controlling the operation of the device and for obtaining physiological data from a patient in which the medical device is implanted. The implanted device also includes a communication circuit for transmitting the physiological data to an external device. A first power source is coupled to the control circuit and provides power to the control circuit. A second power source is coupled to the communication circuit and provides power to the communication circuit.

Implantable medical device with a dual power source

A pacing system and method for providing multiple chamber pacing of a patient's heart, and in particular, pacing programmed for treatment of various forms of heart failure. The system utilizes impedance sensing for determining optimum pacing parameters, e.g., for pacing the left ventricle so that left heart output is maximized. The impedance sensing also is used for determination of arrhythmias or progression of heart failure. Impedance sensing is provided for between selected pairs of the four chambers, to enable optimizing of information for control and diagnosis. In a preferred embodiment of the invention, impedance measurements are obtained for determining the timing of right heart valve closure or right ventricular contractions, and the timing of delivery of left ventricular pace pulses is adjusted so as to optimally synchronize left ventricular pacing with the right ventricular contractions. Impedance sensing in the left heart also provides timing of mechanical contraction, and the pacemaker controls pacing to maintain bi-ventricular mechanical synchronization adjusted for maximum cardiac output.

Four-chamber pacing system for optimizing cardiac output and determining heart condition

An implantable pump apparatus and method of operating the implantable pump for infusing a fluid into a body as described. An expandable fluid reservoir member includes a first end, a second end, an inlet for receiving the fluid from an outside source and an outlet for dispensing the fluid into the body. A first conductor is operably attached to the first end of the expandable fluid reservoir member. A second conductor is operably attached to the second end of the expandable fluid reservoir member. The level of fluid within the expandable fluid reservoir member is determined by measuring an inductance value at the first conductor that is proportional to the distance between the first conductor and the second conductor.

Apparatus and method for measuring the amount of fluid contained in an implantable medical device

An apparatus and method that will allow for external communication, via an external programmer, for positive device identification and for retrieval of device or patient information stored by an implantable medical device with a depleted power source. The external programmer will deliver energy to a secondary power source located inside the implanted device using RF telemetry sufficient to charge up the secondary power source, e.g., a small capacitor. The capacitor will charge up immediately within milliseconds. Once the secondary power source is sufficiently charged, it can be used to power up a controller having the stored information in the implantable medical device. Once the controller is operational, the implanted device will transmit device and patient information to the external programmer via RF telemetry.

Apparatus and method for allowing immediate retrieval for information and identification from an implantable medical device having a depleted power source

There is provided a system and method for continually monitoring the occurrence of contraction during stimulation of skeletal muscle which is employed in a cardiac assist-type system. During delivery of a periodic burst, or train of stimulus pulses, the impedance of the muscle between the electrodes through which the pulses are delivered is monitored, and evaluated to determine whether or not stimulation has been achieved. In a particular embodiment, the impedance and impedance derivative values are accumulated throughout the burst, and assessed to determine whether the impedance change corresponded to a full muscle contraction. In the event of failure to stimulate the muscle to contraction, the system can automatically adjust the pulse output parameters to achieve reliable contraction.

System and method of determining skeletal muscle contraction by serial lead impedance measurements

A system and method for locating an implantable medical device. The system consists of a flat &ldquo;pancake&rdquo; antenna coil positioned concentric with the implantable medical device target, e.g. the drug reservoir septum. The system further features a three location antenna array which is separate from the implantable device and external to the patient. The antenna array features three or more separate antennas which are used to sense the energy emitted from the implanted antenna coil. The system further features a processor to process the energy ducted by the antenna array. The system senses the proximity to the implant coil and, thus, the implant device by determining when an equal amount of energy is present in each of the antennas of the antenna array and if each such ducted energy is greater than a predetermined minimum. When such a condition is met, the antenna array is aligned with the implant coil. Thus the needle port through the antenna array is lined up with the septum of the drug reservoir. Alternative embodiments are further disclosed in which the processor and antenna array are positioned within the implanted device while the coil is external to the patient.

System for locating implantable medical device

A pacing system and method for providing multiple chamber pacing of a patient's heart, and in particular, pacing programmed for treatment of various forms of heart failure. The system utilizes impedance sensing for determining optimum pacing parameters, e.g., for pacing the left ventricle so that left heart output is maximized. The impedance sensing also is used for determination of arrhythmias or progression of heart failure. Impedance sensing is provided for between selected pairs of the four chambers, to enable optimizing of information for control and diagnosis. In a preferred embodiment, impedance measurements are obtained for determining the timing of right heart valve closure or right ventricular contractions, and the timing of delivery of left ventricular pace pulses is adjusted so as to optimally synchronize left ventricular pacing with the right ventricular contractions. Impedance sensing in the left heart also provides timing of mechanical contraction, and the pacemaker controls pacing to maintain bi-ventricular mechanical synchronization adjusted for maximum cardiac output.

Bi-ventricular pacing method

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Limbricht, Netherlands

Robert Leinders