Abbvie Biotechnology Ltd

Other

Abbott Biotechnology Ltd.

Robert L Wong

Walter P Maksymowych

John R Medich

Hartmut Kupper

Rebecca S Hoffman

John C Davis

Christopher T Ritchlin

Renee J Perdok

Michelle P Luo

Eric H Sasso

Joachim Sieper

Phillip Mease

The invention provides methods, uses and compositions for the treatment of psoriatic arthritis. The invention describes methods and uses for treating psoriatic arthritis, wherein a TNF&#x3b1; inhibitor, such as a human TNF&#x3b1; antibody, or antigen-binding portion thereof, is used to psoriatic arthritis in a subject. Also described are methods for determining the efficacy of a TNF&#x3b1; inhibitor for treatment of psoriatic arthritis in a subject.

Uses and compositions for treatment of psoriatic arthritis

The invention provides methods, uses and compositions for the treatment of ankylosing spondylitis (AS). The invention describes methods and uses for treating ankylosing spondylitis, wherein a TNF&#x3b1; inhibitor, such as a human TNF&#x3b1; antibody, or antigen-binding portion thereof, is used to reduce signs and symptoms of ankylosing spondylitis in a subject. Also described are methods for determining the efficacy of a TNF&#x3b1; inhibitor for treatment of ankylosing spondylitis in a subject.

Methods for treatment of ankylosing spondylitis using TNF alpha antibodies

The invention provides a method for determining the efficacy of a TNF&#x3b1; inhibitor, such as a TNF&#x3b1; antibody, or an antigen-binding portion thereof, for treating ankylosing spondylitis (AS), using a collagen degradation biomarker and/or a synovitis biomarker.

Methods and compositions for diagnosing ankylosing spondylitis using biomarkers

Method of treating ankylosing spondylitis

Methods and compositions for determining the efficacy of a treatment for ankylosing spondylitis using biomarkers

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Basking Ridge, NJ, United States of America

Robert L Wong