Wisconsin Alumni Research Foundation

Varigen Biosciences Corporation

Terra Bioworks, Inc.

Robert Joseph Stankey

David Mead

Brian Fox

Richard David Vierstra

Emily Beebe

Cameron Robert Currie

Junrui Zhang

Disclosed herein are recombinant methods of activating expression of one or more biosynthetic gene clusters comprising more than one gene, the method comprising a recombinant DNA expression vector that possess two opposable inducible promoters that drives expression of a biosynthetic gene cluster exogenously from outside of the cluster to produce polyketides or non-ribosomal peptides in a heterologous host.

Expression vector

A heterologous gene cassette useful for creatingspecies with enhanced capability of growing on a cellulosic polysaccharide substrate, wherein the cassette comprises at least two members of the following categories: a) a GH6 gene, b) an AA10 gene, c) a GH48 gene, d) a GH5 gene and e) either (i) a GH9 gene, (ii) a GH9 gene and a GH12 gene, or (iii) a GH12 gene is disclosed.

Method of creating industrial streptomyces with capability to grow on cellulosic polysaccharide substrates

Polynucleotides encoding polypeptides that increase the light sensitivity of plants were identified. Introduction of the polynucleotides into plants produces plants having altered characteristics, such as decreased height, decreased diameter, decreased petiole length, decreased internode length, decreased hypocotyl length, increased hyponasty or enhanced germination.

Plants with altered phytochromes

Growing community of inventors

Madison, WI, United States of America

Robert Joseph Stankey