Devax, Inc.

Biosensors International Group, Ltd.

M.a. Med Alliance Sa

Cardiovascular Dynamics, Inc.

Radiance Medical Systems, Inc.

Robert John Elicker

Jean-Claude Laborde

Jacques Sequin

Ronald Kenichi Yamamoto

Jacques Seguin

Lynn M Shimada

Michael D Crocker

Tien Thuy Nguyen

John Edwin Shulze

Jelle Jurjen Zoethout

Michael Thomas Ahlering

Brett A Trauthen

Jacques R Seguin

Gregg Stone

A coating for an expandable portion of a catheter comprising a lipophilic matrix and a plurality of micro-reservoirs dispersed in the lipophilic matrix is disclosed. The plurality of micro-reservoirs comprises an active agent. A coating formulation and a method for forming the coating are also disclosed. A catheter comprising the coating on the expandable portion and a method for treating a condition are also provided.

Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs

A coating for an expandable portion of a catheter comprising a hydrophobic matrix and a dispersed phase is disclosed. The dispersed phase comprises a plurality of micro-reservoirs dispersed in the hydrophobic matrix, wherein the plurality of micro-reservoirs comprises a first active agent and a first biodegradable or bioerodable polymer. A coating formulation and a method for forming the coating are also disclosed. A catheter comprising the coating on the expandable portion and a method for treating a condition are also provided.

Disclosed is a stent that is useful for treating a vascular bifurcation, the stent having a plurality of segments extending coaxially end to end along a longitudinal axis of the stent from a first end to a second end of the stent, each segment having a plurality of struts extending in a zig-zag pattern around the circumference of the stent, wherein the stent is expandable from reduced diameter to an expanded diameter, the second end of the stent having a larger diameter than the first end when expanded; and an eyelet integrally formed with the segment positioned adjacent the second end, and configured to receive a radiopaque marker therein. The stent provides an improvement over prior stents for treating a vascular bifurcation by allowing the stent to be deployed in the widened transitional zone of a bifurcation such that the second end of the stent is accurately positioned at the carina.

Bifurcation stent and method of positioning in a body lumen

A device and method for treating pathological narrowing of fluid-carrying conduits of the human body (such as blood vessels) in an area of a bifurcation is disclosed. In particular, a stent delivery system configured to carry one or more of a pair of dissimilar stents. At least one of the stents is particularly suited for treating a widened portion of a blood vessel immediately proximal to a bifurcation. The stent delivery system can also include a handpiece adapted to selectively deliver the stents.

Endoprosthesis deployment system for treating vascular bifurcations

A device and method for treating pathological narrowing of fluid-carrying conduits of the human body (such as blood vessels) in an area of a bifurcation is disclosed. In particular, a stent system comprising a pair of dissimilar stents, one of which is particularly suited for treating a widened portion of a blood vessel immediately proximal to a bifurcation. A stent delivery system including a handpiece adapted to selectively deliver the stents is also disclosed.

Endoprosthesis deployment methods for treating vascular bifurcations

A device and method for treating pathological narrowing of fluid-carrying conduits of the human body (such as blood vessels) in an area of a bifurcation is disclosed. In particular, a stent system carries a self expandable noncylindrical stent, which is particularly suited for treating a widened portion of a blood vessel immediately proximal to a bifurcation. A stent delivery system is also disclosed, for delivering the stent such that a larger expanded diameter end of the stent faces the bifurcation, and a smaller expanded diameter end of the stent faces proximally in the main vessel.

Noncylindrical stent deployment system for treating vascular bifurcations

A method of deploying a bifurcation stent at a vascular bifurcation of a main vessel into first and second branch vessels includes: positioning a bifurcation stent at a vascular bifurcation, the bifurcation stent expandable from a reduced diameter to an expanded diameter, the bifurcation stent comprising a first end, a second end, and a marker near the first end, wherein the first end diameter is larger than the second end diameter when the bifurcation stent is expanded, and wherein the bifurcation stent is positioned such that the marker is approximately aligned with a carinal plane at the vascular bifurcation; partially expanding the first end of the bifurcation stent; adjusting the position of the bifurcation stent such that the marker is positioned past the carinal plane and towards the first branch vessel; and deploying the bifurcation stent at the bifurcation. Devices are also disclosed.

Noncylindrical drug eluting stent for treating vascular bifurcations

Noncylindrical stent deployment for treating vascular bifurcations

Disclosed is a focal balloon having at least one reference zone and a focal zone. In one embodiment, the reference zone and focal zone are inflatable to a first generally cylindrical profile at a first pressure. At a second, greater pressure, the focal section expands to a second, greater diameter, while the reference zone remains substantially at the first diameter. In an alternate embodiment, the focal zone and the reference zone are inflatable to their respective predetermined diameters at the inflation pressure, in the absence of constricting lesions or anatomical structures. Both balloons may be utilized to conduct interactive angioplasty to provide real-time feedback about the morphology of the lesion, and both balloons may be utilized to implant or size intravascular stents.

Fixed focal balloon for interactive angioplasty and stent implantation

Disclosed is a tuvular sheath which is adapted to fit coaxially over an inflatable balloon. The sheath functions to alter the expansion characteristics of the balloon. In one preferred embodiment, the sheath converts the inflation profile of a dilatation balloon from a compliant mode to a noncompliant mode. Advantageously, the balloon sheath may be used in stent placement procedures, to accurately size the stent within a body lumen, while providing protection against balloon rupture. In one embodiment, the balloon sheath comprises a two-layered tubular structure, with an outer elastic layer surrounding an inner inelastic layer. Also disclosed are methods of altering the expansion characteristics of a balloon using the balloon sheath.

Growing community of inventors

Santa Margarita, CA, United States of America

Robert John Elicker