Caris Mpi, Inc.

Robert J Penny

Daniel D Von Hoff

Matthew J McGinniss

Alan Wright

David M Loesch

Arlet Alarcon

Ryan P Bender

Traci Pawlowski

Christine Kuslich

Matthew J Mcginnis

Provided herein are methods and systems of molecular profiling of diseases, such as cancer. In some embodiments, the molecular profiling can be used to identify treatments for a disease, such as treatments that were not initially identified as a treatment for the disease or not expected to be a treatment for a particular disease.

Molecular profiling of tumors

A system and method for determining individualized medical intervention for a particular disease state, and especially for cancers, that includes the molecular profiling of a biological sample from the patient, determining whether any molecular findings including one or more genes, one or more gene expressed proteins, one or more molecular mechanisms, and/or combinations of such exhibit a change in expression compared to a reference, and identifying a non-specific disease therapy or agent capable of interacting with the genes, gene expressed proteins, molecular mechanisms, or combinations of such molecular findings that exhibited a change in expression.

System and method for determining individualized medical intervention for a disease state

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Lebanon, IN, United States of America

Robert J Penny