Ventana Medical Systems, Inc.

Roche Sequencing Solutions, Inc.

Roche Molecular Systems, Inc.

Kimantech, LLC

University of Utah Research Foundation

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Robert J Parry

Nils B Adey

Dale B Emery

Rene M Guerrero

Emmanuel Naouri

Peter Romanowich

Leonid Fomin

Mark Herrmann

Katherine B Geiersbach

A system, an instrument, a computer-implemented method, and a clinical workflow for mesodissection of biological specimens on tissue slides by incorporating annotations. An image of an annotated reference slide is acquired and transposed onto a plurality of serial samples on the tissue slides along with the corresponding annotations and metadata. The serial samples are milled based on the annotations, and the milled tissue is automatically collected along with a milling buffer solution inside milling tips, and then dispensed in designated collection vials. The instrument automates the filling of aqueous buffer inside the milling tips and the monitoring of the buffer solution and the sequential filling of the milling tips. The workflow provides an integrated interface that performs tissue annotation, alignment, dissection, tracking, and reporting on a single screen. The degree of precision, ease of use and repeatability will improve PCR and NGS test results, ultimately providing timely patient results.

Automated tissue dissection instrument and methods of using the same

Devices, systems, and associated methods for selectively extracting a material from a sample are provided. In one aspect, for example, a method for selectively extracting biological material from a biological sample can include identifying a region of biological material to be extracted from a biological sample disposed on a substantially planar surface, applying an extraction tool to the region of biological material to disrupt biological material from the biological sample, and dispensing a liquid at the region of biological material. The method can also include aspirating the liquid and the disrupted biological material from the biological sample.

Devices, systems, and methods for extracting a material from a material sample

A liquid dispensing device for a container, and associated systems and methods, are disclosed. The liquid dispensing device can include a penetrating tip configured to penetrate a container, which is configured to have a liquid disposed therein. Relative movement of the penetrating tip and the container toward one another can be operable to create an opening in a portion of the container, and the liquid can dispense from the container through the opening.

Liquid dispensing device

Growing community of inventors

Park City, UT, United States of America

Robert J Parry