Edico Genome Corporation

Ncr Corporation

Lsi Corporation

Tarari, Inc.

Intel Corporation

Illumina Corporation

Teradata Us, Inc.

Paraccel LLC

Teradata Corporation

Evc, Inc.

Lsi Corportion

Robert J McMillen

Michael D Ruehle

Pieter Van Rooyen

David J Chura

M Cameron Watson

Mark Hahm

Rami Mehio

Eric T Lemoine

Chinh Kim Nguyen

Douglas Edward Hundley

Nayan Amrutlal Suthar

John Cooper Roddey

Michael A Faltys

Umesh Ramkrishnarao Kasture

Philip M Neches

Vinay Janardan Naik

Carl A Moran, Jr

A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes an integrated circuit formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the integrated circuit connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. Each subset of the hardwired digital logic circuits is formed in a wired configuration to perform the one or more steps in the sequence analysis pipeline.

Bioinformatics systems, apparatus, and methods executed on an integrated circuit processing platform

A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes a integrated circuit formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the integrated circuit connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. Each subset of the hardwired digital logic circuits is formed in a wired configuration to perform the one or more steps in the sequence analysis pipeline.

Genomic infrastructure for on-site or cloud-based DNA and RNA processing and analysis

A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes a structured ASIC formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the structured ASIC connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. Each subset of the hardwired digital logic circuits is formed in a wired configuration to perform the one or more steps in the sequence analysis pipeline.

Bioinformatics systems, apparatuses, and methods executed on an integrated circuit processing platform

A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes an integrated circuit formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. In various instances, each subset of the hardwired digital logic circuits may be formed in a wired configuration to perform one or more steps a variant call operation.

Bioinformatics, systems, apparatus, and methods executed on an integrated circuit processing platform

A 'dynamic' reference is presented that utilizes population level information to improve reference-based alignment to detect novel, deleterious, or functional variants in clinical sequencing applications. An automatically updated database of known genetic variants is provided to a memory connected with an integrated circuit configured for genetic sequence data with the dynamic reference and reference variants.

Dynamic genome reference generation for improved NGS accuracy and reproducibility

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Carlsbad, CA, United States of America

Robert J McMillen