Smithkline Corporation

Smithkline Beckman Corporation

Smithkline Beecham Corporation

Robert J Gyurik

William D Kingsbury

Michael Thomas Clark

Vassilios J Theodorides

Marianne C Murray

Matthew J Raymond

Sharon K Lewis

Brian G Bagnall

A stabilized complex comprising a growth hormone and an aromatic aldehyde. Specifically, the complex comprises porcine somatotropin and a substituted benzaldehyde and to a method of providing a prolonged release of the somatotropin and improved feed efficiency in animals.

Stabilized somatotropin for parenteral administration

Delayed action dosage unit for releasing medicaments or the like in

A device for effecting the delayed release of an active ingredient comprises a container and, within, a dispersible unit of ingredient, a removable closure and a electrical control circuit for removal of said closure at a designated time to release the active ingredient. Several assemblies are combined to control the administration of veterinary medicaments to ruminant animals as a specific application of the invention.

Delayed action assembly

New anthelmintic compounds, compositions and methods of use are described utilizing 5-cycloalkylthio and oxy-2-carbalkoxyaminobenzimidazole. Methods of preparation involve the reaction of 4-cycloalkylthio- or oxy-o-phenylenediamine with methyl cyanocarbamate in aqueous miscible organic solvents.

5-Cycloalkyl thio- and oxy-2-carbalkoxyaminobenzimidazoles

New anthelmintic compositions and methods of use are described utilizing 5-cycloalkylthio and oxy-2-carbalkoxyaminobenzimidazoles as active ingredients.

Methods and compositions using 5-cycloalkylthio- and

New methyl benzimidazolecarbamate compounds having a heterocyclic thio or oxy moiety at position 5, useful as anthelmintics are described. Methyl-5-(pyridylthio)- and 5-(pyridylmethylthio)-benzimidazolecarbamates are preferred.

Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles

Methyl 5-propylthio-2-benzimidazolecarbamate is the active ingredient for methods and compositions affording enhanced activity against gastrointestinal helminths in commercial or pet animals. It is also active against lungworms, cestodes and flukes in animals.

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Downingtown, PA, United States of America

Robert J Gyurik