Johnson Matthey Public Limited Company

Other

Robert Hogan

Ronald Rossi

Lee Jonathan Silverberg

Ramesh M Shah

Throttle-at-valve apparatus, internal combustion engines employing throttle-at-valve apparatus, and methods of throttling an internal combustion engine using a throttle-at-valve apparatus, where the throttle-at-valve apparatus includes a throttle slide body disposed within a throttle slide cavity that is defined between and in fluid communication with both an unobstructed air intake passage and an intake valve of an internal combustion engine, where the air flow from the air intake passage to the intake valve is regulated by the reciprocal movement of the throttle slide body within the throttle slide cavity.

Throttle-at-valve apparatus

An example embodiment of an all-stroke-variable internal combustion engine may include a piston slidably positioned within an engine cylinder for asymmetrical reciprocation and a primary crankshaft and a half-speed crankshaft to be operatively engaged for rotation of the half-speed crankshaft at half of a speed of the primary crankshaft, wherein the rotation of the half-speed crankshaft at half of the speed of the primary crankshaft to result in the asymmetrical reciprocation of the piston so as to produce a stroke length that is independently variable over four distinct strokes of a full cycle of the all-stroke-variable internal combustion engine.

Zero intrusion valve for internal combustion engine

Pivotal drive system for internal combustion engine

All-stroke-variable internal combustion engine

A composition comprising a high purity cannabinoid, an acid, and a pharmaceutically-acceptable solvent achieves room temperature stability for over 24 months. The acid improves the stability of the composition and the solvent enhances the solubility of the acid, thereby allowing the acid to have an improved stabilizing effect on the highly pure cannabinoid. Preferably, the solvent is an alcohol and, more preferably, the composition contains an oil. A method for making the composition includes combining the cannabinoid and the solvent and evaporating a portion of the solvent, along with adding an acid to the composition, before, during, or after the evaporating step. A method for making and storing the composition includes storing the composition in a manner adapted to maintain its stability. Pharmaceutical dosage forms include a formulated composition, such as having the oil. A method of treating a subject comprises administering to the subject the dosage form.

Method for making and storing stable cannabinoid compositions and method for treatment using such compositions

The present invention provides a method for the purification of a prostaglandin by supercritical fluid chromatography, said method comprising the use of a stationary phase and a mobile phase comprising carbon dioxide, provided that when the stationary phase is unmodified silica gel, the prostaglandin is not luprostiol. The invention also provides prostaglandins obtainable by the method.

Method for the purification of prostaglandins

Stable cannabinoid compositions and methods for making and storing them

A composition comprising a tetrahydrocannabinol compound, a solvent and an acid, wherein the tetrahydrocannabinol compound may be &#x394;tetrahydrocannabinol, (&#x2212;)-&#x394;-trans-tetrahydrocannabinol or a side chain alkyl derivative of either compound, the solvent may be an oil or C-Calcohol (e.g. sesame oil or ethanol), and the acid may be an organic acid or a mineral acid.

Growing community of inventors

West Grove, PA, United States of America

Robert Hogan