Leland Stanford Junior University

Robert Hofstadter

Edward Rubenstein

E Barrie Hughes

Non-invasive angiography is provided through use of monochromatized synchrotron radiation in a dichromographic procedure. A small quantity of an iodinated compound is introduced into the blood stream of a patient. An X-ray picture of a blood vessel such as the coronary artery can be produced by directing synchrotron radiation from a storage ring source at first and second selected wavelengths or energy levels through the blood vessel, detecting the attenuated radiation to obtain first and second signals representative of the attenuated radiation, and logarithmically subtracting the two signals to essentially eliminate all background contrast. Due to the K-absorption edge of iodine the resulting signal will emphasize the blood vessel containing the iodine.

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Stanford, CA, United States of America

Robert Hofstadter