Basf Aktiengesellschaft

Other

Abbvie Deutschland Gmbh and Co Kg

Abbott Gmbh & Co Kg

Basf Se Corporation

Robert Heger

Helmut Auweter

Jörg Breitenbach

Heribert Bohn

Karl Siemensmeyer

Dieter Horn

Jörg Rosenberg

Eric D Carlson

Ralph B Nielsen

Rainer Dyllick-Brenzinger

Wolfgang Schrof

Bernd Siegel

Gunther Berndl

Bernd Liepold

Dirk Simon

J&ouml;rg Breitenbach

Primoz Lorencak

Thomas W&uuml;nsch

G&uuml;nter Oetter

Wilma M Dausch

Volker Laux

Dieter Herr

Sigrid C Kuebler

Walter M&auml;chtle

Georg Konrad Zwissler

Petro Miroslav

Thomas Wünsch

R&uuml;diger Iden

Chang Han-Ting

Michael Stadler

Michael Seufert

G&uuml;nther Glas

Peter Wilke

Ulrike Schlösser

Jorg Rosenberg

Jorg Breitenbach

The present invention relates to self-emulsifying formulations based on an active ingredient component and a formulation base with a lipid component and with a binder component and to the use of this formulation as dosage form in the life science sector. The invention also describes a process for producing self-emulsifying formulations by mixing the formulation components to form a plastic mixture and, where appropriate, to manufacture the formulations as dosage form advantageously by use of melt extrusion. The formulations spontaneously form emulsions in water or aqueous media.

Self-emulsifying active substance formulation and use of this formulation

Nanoparticulate preparations of pharmaceutical and cosmetic active substances with a core-shell structure, whereby the active substance is present in an X-ray amorphous form, together with a polymer matrix and the shell consists of a stabilizing sheathing matrix.

Nanoparticulate core shell systems and the use thereof in pharmaceutical and cosmetic preparation

The present invention relates to formulations based on at least one heparin, glycosaminoglycan or heparinoid and on a formulation base with a lipid component and a polymer component. The use of this formulation as drug form for oral administration of at least one heparin, glycosaminoglycan or heparinoid, and also a process for producing the formulations by mixing the formulation components to form a plastic mixture and, where appropriate, to manufacture the formulations as drug form, advantageously using melt extrusion, are described. The lipid component advantageously has active ingredient-promoting properties, while the polymer component is soluble or swellable. At least parts of the lipid component are embedded in a polymer matrix, preferably in the form of a molecular dispersion. The formulations can form emulsions in water or aqueous liquids.

Formulation based on heparin, glycosaminoglycan or heparinoid, use of the formulation and the formulation base

Dye-containing polymer particles of at least one dye in a matrix of an essentially water-insoluble polymer and having an average particle size within the range from 5 nm to 5 &#x3bc;m are prepared by a process which comprises precipitating the dye-containing polymer particles from a solution of the polymer and of the dye in a water-miscible organic solvent by addition of an aqueous phase thereto.

Polymer particles containing dye

Antifoams and/or deaerators are based on oil-in-water emulsions which contain, in the hydrophobic oil phase, at least one compound effective as an antifoam and/or deaerator and, if required, further components, the oil-in-water emulsions containing from 0.01 to 3% by weight of a water-soluble, amphiphilic copolymer having acid groups or of a water-soluble salt thereof as a stabilizer.

Defoamer and/or deaerator based on oil-in-water dispersions

The present invention relates to a set of (co)polymers, dispersion formulations, solid solutions and formulation conditions able to disperse a dye selected from the group of a monoazo dye, quinophthalone dye and an anthraquinone dye in a stable nanoparticular form in an aqueous medium.

Surface active random radical (co)polymer and dispersion method for using the same

A test system for characterizing the compatibility of bioactive substances with polyvinylpyrrolidones in a solid dispersion consisting of one or more bioactive substances and 1,3-bis(1-pyrrolidonyl)butane.

Test system for characterizing the compatibility of bioactive substances and polyvinylpyrrolidone

The invention relates to aqueous dispersions of sparingly water-soluble or water-insoluble organic UV filter substances, which comprise at least one sparingly water-soluble or water-insoluble organic UV filter substance as colloidally disperse phase in amorphous or partially amorphous form.

Aqueous dispersion of water-insoluble organic UV filter substances

The dyes have an average particle size within the range from 5 nm to 1 &mgr;m and a variance of less than 50%. They are especially useful for ink-jet ink preparations.

Precipitated water-insoluble colorants in colloid disperse form

Growing community of inventors

Heidelberg, Germany

Robert Heger