Cornell Research Foundation Inc.

Cornell University

Max-planck-gesellschaft Zur F&#xf6;rderung Der Wissenschaften E. V.

Vision Quest Industries Incorporated, Doing Business As Vq Orthocare

Robert Gilmour

Valentin I Krinski

Eberhard Bodenschatz

Stefan Luther

Flavio H Fenton

Jeffrey J Fox

Mark Riccio

Valentin Krinski

Flavio Fenton

For terminating a high frequency arrhythmic electric state of a heart an electric signal representative of the present electric state of the heart is obtained. From the electric signal a dominant frequency of the present electric state is determined, and from the dominant frequency it is determined whether the present electric state of the heart is a high frequency arrhythmic electric state displaying at least one rotating wave. Further, a dominance level indicative of how dominant the dominant frequency is in the high frequency arrhythmic electric state is determined from the electric signal. Depending on the at least one dominant frequency, at least one series of electric pulses at intervals is generated. The electric pulses are applied to the heart starting at a point in time at which the dominance level exceeds a predefined threshold value for the heart being in a determined high frequency arrhythmic electric state.

Apparatus for terminating a high frequency arrhythmic electric state of a heart

For terminating a high frequency arrhythmic electric state of a biological tissue an electric signal representative of the present electric state of the biological tissue is obtained. From the electric signal a dominant frequency of the present electric state is determined, and from the dominant frequency it is determined whether the present electric state of the biological tissue is a high frequency arrhythmic electric state. Further, a dominance level indicative of how dominant the dominant frequency is in the high frequency arrhythmic electric state is determined from the electric signal. Depending on the at least one dominant frequency, at least one series of electric pulses at intervals is generated. The electric pulses are applied to the biological tissue starting at a point in time at which the dominance level exceeds a predefined threshold value for the biological tissue being in a determined high frequency arrhythmic electric state.

Apparatus for and method of terminating a high frequency arrhythmic electric state of a biological tissue

The present invention relates to evaluating the effect of physiological conditions on the occurrence of ventricular fibrillation, identifying strategies for treatment or prevention of ventricular fibrillation or ventricular tachycardia, and evaluating a subject for induction of ventricular fibrillation from a condition of ventricular tachycardia.

Method of identifying strategies for treatment or prevention of ventricular fibrillation and ventricular tachycardia

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Ithaca, NY, United States of America

Robert Gilmour