Abbott Laboratories Corporation

Robert George Stein

Aldo Joseph Crovetti

Terry Lee Couch

Donald Sykes Kenney

Leo Ralph Swett

Don Murl Lynch

James D Ratajczyk

George W Carter

Raymond John Michaels

Hermann Faubl

Novel O-alkylsilyl derivatives of macrolide antibiotics are disclosed. These compounds have markedly superior taste properties when compared to the corresponding parent compounds.

Erythromycin A silylated compounds and method of use

It has been found that substituted aminoacetonitriles of the structure ##STR1## wherein X and Y, independently, stand for hydrogen, halogen, loweralkyl, loweralkyloxy, nitro or CF.sub.3 ; R is hydrogen or methyl; and R' is hydrogen or loweralkyl are excellent insect ovicides.

Ovicides

This invention provides a method for the control of mollusks by treating said mollusk or its habitat with a synergistic composition including O,O-dialkyl-O-(3-benzothienglyoxylonitrile oximino)phosphate of the structure ##STR1## wherein each R is an alkyl group of 1-4 carbon atoms and at least one other known molluscicide.

Molluscicide compositions and methods of use

It has been found that compounds of the structure ##STR1## wherein X is O, S or SO.sub.2, R represents H or one or more halogen, loweralkyl, --CH.dbd.CH--CH.dbd.CH--, CN, NO.sub.2, loweralkyloxy, loweralkylcarbonyl or loweralkylmercapto, R' is H, loweralkyl, benzyl or R', and R' is CH.sub.2 C.tbd.CH, CMe.sub.2 C.tbd.CH or CHMeC.tbd.CH are excellent insect ovicides.

New agriculturally useful compounds are described which are the 2,6-dibromo- or -dichloro- iso- nicotinoyl derivatives of aminoacids.

Herbicides derived from dihalo isonicotinoyl derivatives of amino acids

It has been found that compounds of the structure ##STR1## wherein 'pyr' stands for 2-, 3-, or 4-pyridyl; Z is CO or (CH.sub.2).sub.n ; n is 0, 1 or 2; R is hydrogen, halogen, loweralkyl, loweralkyloxy, nitro, or hydroxymethyl; and R' is hydrogen or halogen are excellent insect ovicides.

Certain ovicidal piperazines

Compounds of the formula ##STR1## wherein R is phenyl, benzyl, 1-isopropylbenzyl wherein each of said aromatic rings may carry a chlorine substituent, ##STR2## R' is H, --C.tbd.N or --C.tbd.CH; R' is chlorine, bromine, fluorine or methyl; X and Y both but independently are H or loweralkyl; and Z is phenyl or benzyl which may carry an optional aromatic chlorine substituent, have been found to be excellent insecticides, ovicides and/or miticides.

Insecticidal pyrazole-4-methanol esters

Compounds of the formula ##STR1## and X is hydrogen, halo, alkyl, cyano or nitro, Y is oxygen or sulfur and R is lower alkyl, have been found to be excellent pesticides.

Phosphoramidates and thiophosphoramidates as pesticides

Biodegradable insecticides having the formula: ##STR1## where X, Y and R are different, and X and Y are selected from the group consisting of hydrogen, halo, lower alkyl and lower alkoxy, and R is selected from the group consisting of nitrogen, oxygen, sulfur and sulfone.

.alpha.-Trichloromethyl thenyl phenylethers and sulfides

Covers use of O-substituted thiophene oxime carbamates as antibacterial and antifungal agents.

Certain O-substituted thiophene oxime carbamates used as antibacterial

.alpha.-Trichloromethyl thenyl anilines as biodigradable insecticides

Covers a method of inducing abscission of fruit by applying a chemical composition containing an effective amount of a 4-nitropyrazole as the active ingredient in an agronomically acceptable carrier. Also covers certain 4-nitropyrazoles.

4-Nitropyrazoles

Biodegradable insecticides and molluscicides having the formula ##STR1## where X is selected from the group consisting of hydrogen, halo, lower alkyl and lower alkoxy; and Y is selected from the group consisting of hydrogen, halo, lower alkyl (C.sub.1 -C.sub.8), lower alkoxy (C.sub.1 -C.sub.8) and halo lower alkyl.

.alpha.-Thienyl and .alpha.-substituted thienyl, phenyl and substituted

A series of acylphosphonate esters have been found which prevent or relieve some of the ill effects of UV exposure to human skin.

Acylphosphonate esters

The invention covers the use of O,O-diethylthionophosphonyl-.alpha.-oximino-5-chloro-2-thienyl acetonitrile as a pesticide.

Growing community of inventors

Kenosha, WI, United States of America

Robert George Stein