Dowelanco

Eli Lilly and Company

Semafore Pharmaceuticals, Inc.

Other

Dow Agrosciences LLC

Robert G Suhr

Glen P Jourdan

Barry A Dreikorn

Eriks V Krumkalns

Joseph R Garlich

Donald L Durden

Mary Patterson

Michael J Coghlan

Jingdong Su

Peter Lee Johnson

Harold M Taylor

Francis Eugene Tisdell

Donald H Devries

James Todd Pechacek

Wendell R Arnold

Maurice C Yap

John L Miesel

Christopher Thomas Hamilton

Neil Vincent Kirby

Ronald E Hackler

George W Johnson

Mary L Ash

Carl P Denny

Ronnie G Edie

Brian R Thoreen

Sylvester V Kaster

Christopher J Hatton

Gary D Stockdale

The invention provides novel prodrugs of inhibitors of PI-3 kinase. The novel compounds are LY294002 and analogs thereof comprising a reversibly quaternized amine.

PI-3 kinase inhibitor prodrugs

The invention provides prodrugs of inhibitors of PI-3 kinase. The compounds are LY294002 and analogs thereof comprising a reversibly quaternized amine.

3-(Substituted phenyl)-5-(substituted heterocyclyl)-1,2,4-triazole compounds are useful as insecticides and acaricides. New synthetic procedures and intermediates for preparing the compounds, pesticide compositions containing the compounds, and methods of controlling insects and mites using the compounds are also provided.

3-(substituted phenyl)-5-(substituted heterocyclyl)-1,2,4-triazole compounds

3-(Substituted phenyl)-5-(thienyl or furyl)-1,2,4-triazole compounds are useful as insecticides and acaricides. New synthetic procedures and intermediates for preparing the compounds, pesticide compositions containing the compounds, and methods of controlling insects and mites using the compounds are also provided.

3-(substituted phenyl)-5-(thienyl or furyl)-1, 2, 4-triazole compounds

Substituted quinazolines of the formula (1): ##STR1## wherein: R.sup.1 to R.sup.4 are independently H, halo, (C.sub.1 -C.sub.4) alkyl, branched (C.sub.3 -C.sub.4) alkyl, halo (C.sub.1 -C.sub.4) alkyl, (C.sub.1 -C.sub.4) alkoxy, NO.sub.2, or NH.sub.2,

Quinazoline derivatives

Compounds of the formula (I): ##STR1## wherein: Het is pyridyl, pyrazinyl, pyrimidinyl, or pyridizinyl, optionally substituted with one or more groups selected from halo, lower alkyl, lower alkoxy, haloalkyl, haloalkoxy, NO.sub.2, CN, and lower alkoxy-carbonyl;

4-(2-(4-(2-pyridinyloxy)phenyl)ethoxy)quinazoline and analogues thereof

The compounds of the formula: ##STR1## wherein the substituents are herein below defined; are plant fungicides, insecticides, and miticides.

Quinoline derivatives

The compounds of the formula: ##STR1## where the substituents are herein below defined, are fungicides, insecticides, and miticides.

Substituted quinolines and cinnolines

Fungicidal compositions comprise a combination of two fungicides, one of which is a quinoline or cinnoline compound of the formula (1) ##STR1## the substituents being as described in the specification.

Quinoline and cinnoline fungicide compositions

A method of inhibiting a nematode population which comprises applying to the locus of a nematode, a nematode inactivating amount of a compound of the formula (1):

Quinoline nematicidal method

Compounds of the formula (1) ##STR1## the substituents are described in the specification. The compouns of formula (I) are plant fungicides.

Quinoline and cinnoline fungicides

A fungicidal method which comprises applying to the locus of a plant pathogen a fungicidally effective but non-phytotoxic amount of a compound of the formula (1) ##STR1## wherein: R.sup.1 to R.sup.4 are independently

Substituted quinolines and cinnolines as fungicides

The present invention is directed to 1-benzoyl-3-(aryloxy- or arylthio-pyridinyl)urea compounds useful as insecticides.

1-Benzoyl-3-(aryloxy- or arylthiopyridinyl) urea compounds

A class of 1-alkyl-3-phenylpyridinium salts are useful herbicides. The compounds bear a meta-substituent on the phenyl ring and optional 4- and 5-substituents.

Growing community of inventors

Greenfield, IN, United States of America

Robert G Suhr