Other

Robert G Glushkov

Mikhail D Mashkovsky

Irina A Ivanova

Vladimir G Granik

Antonina I Polezhaeva

Jury G Bobkov

Lidia F Roschina

Roza B Parimbetova

Alexandr S Losev

Tatyana V Stezhko

Grigory Yakovlevich Avrutsky

Leonid N Gerchikov

Vera A Volskova

Anatoly Boleslavovich Smulevich

Antonida V Zaitseva

By Galina Magidson

By July Magidson, Administrators

Nataiia I Andreeva

Onisim J Magidson, Deceased

Natalia Ivanovna Andreeva

Valentina Vasilievna Gromova

Serafima S Liberman

A novel compound, namely, 1-thiocarbamylmethylpyrrolidine-2-thione has the following formula: ##STR1## A process for preparing said compound comprises reacting a derivative of pyrrolidone-2 of the general formula: ##STR2## wherein R is nitrile or carbamoyl, with phosphorus pentasulphide in an inert non-polar solvent at a temperature above room temperature, followed by treatment of the resulting precipitate with water upon boiling and isolation of the desired product. The compound according to the present invention exhibits antihypoxic and nootropic activity.

1-thiocarbamylmethylpyrrolidine-2-thione, process for preparing

1-Thiocarbamoylmethylpyrrolidine-2-thione, medical compositions of, and

New tetracyclic compounds, containing indole nucleus in their structure, having the general formula ##STR1## where R is hydrogen, alkyl, or alkoxyl, R' is an alkyl, and m and n are 2 or 3. The said compounds react with organic and mineral acids to form salts readily soluble in water. The method for preparing the said compounds consists in cyclization of lactams, having the general formula ##STR2## where R, R', m and n are as specified above, or of their hydrochlorides by phosphorus oxychloride.

Pyrazino (1,2,3-ab)-.beta.-carboline derivatives and salts thereof and

A psychotropic medicinal preparation comprising a therapeutically effective amount of an active principle which is a salt of 3-methyl-8-methoxy-3H, 1,2,5,6-tetrahydropyrazino-[1,2,3]-ab-.beta.-carbolin, and a pharmaceutical carrier therefor. The medicinal preparation is employed in the form of tablets or solutions, the amount of the active principle being 0.025 gm in the tablets and 0.0125 to 0.025 gm in the solutions. The medicinal preparation of the invention is designed for the treatment of depressions and other psychic disorders.

Psychotropic medicinal preparation

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Moscow, Russia

Robert G Glushkov