Boston Scientific Scimed, Inc.

Scimed Life Systems, Inc.

Eclipse Surgical Technologies, Inc.

Ethicon, Gmbh

Ethicon Endo-surgery, Inc.

Cardiac Pathways Corporation

Robert F Bencini

Frank W Ingle

Jon Wohlgemuth

Josef Vincent Koblish

Russell B Thompson

James Mazzone

Katie Messing

Brandon J Shuman

Peter Franklin Campbell

Rebecca Tin

Bernard J Durman

Miriam H Taimisto

Richard Dean Phipps

Paul A Roche

Jonathan A Wohlgemuth

Dennis D Jamiolkowski

Richard L Mueller

Isaac J Kim

David G Lawrence

Richard C Smith

Mark L Pomeranz

Leslie Hamilton

Katie L Krueger

David T Lawrence

Byron Chun

Darrell L Rankin

Loren D Stirling

Richard Lardner

Susan M Pietroski

Edward M Gillis

Mark Forrest

Harold A Heitzmann

Patricia Chen

Siew-Hung Tee

Apparatus and methods for performing cryogenic ablation of tissue and adjusting the size and/or location of a cryogenic cooling region. A cooling assembly may include tubes for dispensing and exhausting a coolant or refrigerant. One or both of the tubes may be moved, e.g., slidably adjusted, in order to adjust the location or size of a cryogenic ablation region. The cooling assembly may be integrated into cryogenic ablation devices including a cryogenic balloon device that includes an inner inflatable balloon and another balloon that is at least partially wrapped around the inner balloon and carries refrigerant for performing cryo-ablation. Electrodes permit electrical mapping of tissue before or after cryo-ablation to verify success of the procedure.

Apparatus and methods for cryogenically ablating tissue and adjusting cryogenic ablation regions

A cryotherapy system includes a cryotherapy catheter having an inflatable balloon portion and a pressure regulator. The inflatable balloon portion includes an outer balloon and an inner balloon within the outer balloon. The inner balloon is configured to receive during a cryotherapy procedure a cryogenic agent for extracting heat from body tissue at a desired location. The inflatable balloon portion is at a distal end of the cryotherapy catheter. The pressure regulator is adapted to maintain a positive pressure between the inner balloon and the outer balloon during a cryotherapy procedure.

Nested balloon cryotherapy

In some implementations, a method of ablating body tissue includes (a) locating an inflatable balloon portion of a cryotherapy balloon catheter at a treatment site internal to a patient's body, and inflating the inflatable balloon portion; (b) employing electrodes that are disposed on an expandable surface of the inflatable balloon portion to electrically characterize body tissue at the treatment site; (c) ablating the body tissue by supplying a cryotherapy agent to the inflatable balloon portion to cool the body tissue to a therapeutic temperature; (d) employing the electrodes to determine whether the ablating caused desired electrical changes in the body tissue; and (e) repeating (c) and (d) when it is determined that the ablating did not cause the desired electrical changes.

Balloon catheter with flexible electrode assemblies

Disclosed herein, among other things, are methods and apparatus related to radio frequency (RF) ablation catheters. The present subject matter provides a method for forming an ablation catheter having a balloon at a distal end of the catheter. The method includes applying a band of conductive material to an outer surface of the balloon. The band of conductive material is adapted to provide one or more electrodes for radio frequency ablation therapy. A distal end of a lead is connected to the band of conductive material. The balloon is inverted, so that the inverted balloon includes the band of conductive material on an inside surface. According to various embodiments, the balloon includes a semi-permeable or hydro-able membrane.

Inverted balloon RF ablation catheter and method

Disclosed herein is a catheter device sized and shaped for vascular access that has an elongate body extending between a proximal end and a distal end. Further, the elongate body has at least one inner lumen configured to receive a fluid. The catheter also has an ablation electrode configured to provide ablative energy, wherein the electrode is located distally along the elongate body and includes a passageway fluidly connected to the lumen of the elongate body. Also, the catheter has a sensor configured to provide a signal representative of temperature, and an insulating chamber extending at least partially about the ablation electrode and configured to at least partially insulate the sensor.

Insulated ablation catheter devices and methods of use

Described herein are various methods and devices for delivering cryoablative therapy. One such device includes a cryoablation chamber and a volume displacement chamber. In use, the volume displacement chamber can be expanded to occupy a non-therapeutic volume.

Ablation devices and methods of use

Described herein are various methods and devices for delivering cryoablative therapy. Various ablative patterns can be produced by the devices, including, linear ablation patterns. One exemplary device includes a cryoablation chamber and a volume displacement chamber. In use, the volume displacement chamber can be expanded to support the cryoablation chamber.

Linear ablation devices and methods of use

A cryotherapy catheter can include an elongate member and an inflatable balloon portion at a distal end of the elongate member. The inflatable balloon portion can have an external surface and an interior chamber, and the external surface can include a cooling region and a thermally insulated region. The interior chamber can be configured to receive during a cryotherapy procedure a cryogenic agent for extracting heat from body tissue that is in contact with the cooling region. A thermal profiling component can be disposed in the interior chamber and configured to thermally insulate the thermally insulated region from the cryogenic agent to minimize heat extraction by the cryogenic agent from body tissue that is in contact with the thermally insulated region.

Providing cryotherapy with a balloon catheter having a non-uniform thermal profile

An apparatus including an elongate body having a lumen extending therethrough and a steering wire associated with the distal portion of the elongate body.

Steerable device for introducing diagnostic and therapeutic apparatus into the body

An apparatus including an elongate body having a lumen extending therethrough and a steering wire, having a distal portion defining a non-circular cross-section, associated with the distal portion of the elongate body.

A medical device for use by an operator to perform a medical procedure in a body includes a handle to be held by the operator, a shaft attached to the handle and an actuating assembly to control functions associated with the medical procedure. The shaft includes an operative distal portion to perform a medical procedure in the body. The medical device may be part of an ablation catheter system that is programmed to correlate one or more functions with the actuation of the actuating assembly. Multiple actuating assemblies may be provided. Each actuating assembly may be a button. Other types of actuating assemblies may also be used, such as switches or a trackball. The actuating assembly may also be provided on a sleeve that may be selectively attached to the handle of the catheter or the physician operating the catheter, for example.

Medical device control systems

Growing community of inventors

Sunnyvale, CA, United States of America

Robert F Bencini