Eli Lilly and Company

Robert Eugene Stratford, Jr

Wayne Douglas Luke

Kerry John Hartauer

Brian Weston Dalder

Gordon Nelson Arbuthnot

Paul Leslie Ornstein

Thomas John Bleisch

Edward Louis Mattiuz

This invention provides compounds of formula I and pharmaceutically acceptable salts and solvates thereof, characterized that the compound is in particulate form and having a specific size range. The present invention further provides pharmaceutical compositions containing or formulated using compounds of formula I, and the use of such compounds for alleviating human pathologies, including osteoporosis, serum lipid lowering, and breast cancer.

Benzothiophenes, formulations containing same, and methods

This invention provides compounds of formula Iand pharmaceutically acceptable salts and solvates thereof, characterized that the compound is in particulate form and having a specific size range. The present invention further provides pharmaceutical compositions containing or formulated using compounds of formula I, and the use of such compounds for alleviating human pathologies, including osteoporosis, serum lipid lowering, and breast cancer.

The present invention relates to novel prodrug forms of 3S,4aR,6S,8aR-6-(((4-carboxy)phenyl)methyl)-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid, to pharmaceutical compositions containing the prodrug forms, and to methods of using the prodrug forms.

Diester prodrugs of a decahydroisoquinoline-3-carboxylic acid

Benzothiophenes formulations containing same and methods

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Carmel, IN, United States of America

Robert Eugene Stratford, Jr