Nanosys, Inc.

Robert Enzerink

R Hugh Daniels

J Wallace Parce

Robert S Dubrow

Jay L Goldman

Vijendra Sahi

Esther Li

The present invention relates to treating of reflective surfaces to prevent fouling. The present invention also relates to reflective materials treated to prevent fouling, as well as methods of using such reflective materials.

Non-fouling surfaces for reflective spheres

The invention relates to non-fouling hydrophobic reflective surfaces for a variety of applications which in one embodiment related to medical device applications comprises a method of performing a medical procedure using a surgical navigation system which includes the steps of placing one or more reflective spheres on a surgical instrument or apparatus, the reflective spheres comprising a hydrophobic coating on a sub-micron structured surface of the spheres, wherein the spheres substantially maintain their reflective properties after the spheres are contacted with a biological fluid; shining light on the reflective spheres; capturing reflected light from the spheres with a camera or other device; and registering and/or tracking a location and/or position of the spheres.

Methods, systems, and apparatuses for nanomaterial-enhanced hemostatic medical devices are provided. Hemostatic materials and structures are provided that induce coagulation of blood at a wound/opening caused by trauma, a surgical procedure, ulceration, or other cause. The hemostatic materials and structures may incorporate nanostructures and/or further hemostatic elements such as polymers and/or glass beads. The hemostatic materials and structures may be resorbable. Example embodiments include hemostatic bandages, hemostatic plugs, and hemostatic formulations.

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Davis, CA, United States of America

Robert Enzerink