Washington University

Other

Particle and Coating Technologies, Inc.

Csl Limited

Eka Nobel Ab

Continental White Cap, Inc.

A.e.c. Societe De Chimie Organique Et Biologique

Noram Technology, Ltd.

Robert E Sparks

Norbert S Mason

Irwin C Jacobs

George Spector

Michael Center

Hans Olof Lagnemo

Robert J Heilman

Pierre Autant

John Cooper Cox

Andre Cartillier

Raymond Pigeon

Daniel M Carson

Kenneth Hillel Peter Harris

Mariam M Wahab

A system and method for producing foundry quality sand from non-conventional starting materials through the combination of oolitization and classification. Incoming particulate matter is first directed into a controlled energy attrition unit where the particles are made to collide with one another. Such collisions clean and round the particles by chipping away surface projections and coatings without crushing the particles. The particle stream is then directed through a multi-fraction classifier where it is separated into two or more useable grades of foundry sand. An air classifier is preferred for the classification stage.

Products for the manufacture of molds and cores used in metal casting and a method for their manufacture and recycle from crushed rock

An air classifier with enhanced air flow which maybe used for the simultaneous recovery of two or more distinct grades of foundry quality sand from a single sand stream. The air classifier exhibits improved performance by drawing into the classification chamber, through the use of suction, incoming air through a honeycomb followed by a screen section having two or more screens. The honeycomb removes swirl in the air and the screens slow down the fast moving air more than the slow moving air. After passing through the screens, the velocity profile of the air in the chamber is flat across the inlet flow path and, as a result, improved classification performance is achieved. Classification performance may be further enhanced through the use of a vibrating screen feeder for spreading the incoming particle stream before entrainment in the air flow within the classifier and through upward flowing air in one or more product receiver sections.

Air classifier system for the separation of particles

A method of producing a fast-dissolving pharmaceutical delivery device of moderate strength. The delivery device is a fully formed tablet composed of readily available sugars, strength polymers and a volatilizable excipient along with an active ingredient and optional flavorings. The tablet as made will disintegrate in an aqueous medium such as saliva in under 15 seconds, making mastication unnecessary or at least requiring only one or two bites on the tablet. Essential to the invention is the easily obtainable particle size ranges of the sugars and the volatilizable excipient which promotes optimum release and tablet strength. The invention also allows for effective taste masking of the active ingredient with standard particle coating techniques.

Method of producing porous tablets with improved dissolution properties

Spray dried vaccine preparation comprising aluminium adsorbed immunogens

The present invention relates to particles having a core comprising a peroxy compound and a hydrophobic coating comprising:

Bleaching agent

This relates to the provision of a vacuum actuated button type closure with a tamper indicating arrangement which will visually indicate when a container has been opened or more particularly when the vacuum within a vacuum packed container has been lost. The deflectable button of the closure is utilized to squeeze a dye from a sponge like member into a layer of absorbent material so as to color the absorbent material. The absorbent material, in turn, is provided with non-absorbent areas which define indicia to indicate that an associated container has been opened. The layer of absorbent material is carried by an arched cross sectional cover and in several forms of the cover, a central portion of the cover is downwardly deformable under pressure to move the layer of absorbent material from an inoperative position to a lowered position for cooperation with the sponge like member when the button returns to its up position to effect the flow of the dye from the sponge like member into the layer of absorbent material.

Tamper indicating means for vacuum closures

A composition which is stable in a medium in which the pH is greater than or equal to 5.5 and which permits the release of an active substance in a medium in which the pH is less than or equal to 3.5, comprising the active substance, which contains inclusions of, or which is completely or partially covered by, a pH sensitive material whose extent and/or rate of swelling is greater in an acidic medium than in a neutral medium, and a coating of a hydrophobic layer.

Composition for feeding ruminants

A method of melt granulation for powdery material is disclosed wherein the powdery material is discharged onto the upper surface of a heated rotary spreader for migration under centrifugal force to the periphery of the spreader accompanying by melting of a portion of the material and enrobing of non-melted particles by the melted material for discharge as enlarged granules from the periphery of the spreader. To improve the quality of the granules produced, the feed material is supplied to the spreader at two separate locations. The first location is the central portion of the spreader to provide the melted material and the second location is adjacent to the periphery of the spreader. The spreader is preferably in the form of a concave bowl or inverted truncated cone or dish. Feed material is supplied to the first location by a screw feeder extending down the side of the dish and at the second location by a rotary vaned distributor located within the dish which radially flings the feed material onto the inclined dish wall. The process and apparatus is particularly useful for the production of non-sticky granules which are difficult to form when a single central feed of material is used.

Method and apparatus for granulation and granulated product

Method and apparatus for the formation of granules of a larger size or mass of a desired range from a feed stock of smaller particles comprising feeding a meltable powdery material to be granulated, or a non-meltable powdery material with a meltable binder to the surface of a rotating spreader means in the form of a disk or bowl, at least a portion of which has been heated to a temperature above the melting point of the meltable component of the feed material wherein the rate of feeding, the energy input to the spreader means and the rotational speed of the spreader means are controlled so that there is sufficient time for at least a partial melting of the meltable component of the feed material substantially solely by contact with the heated surface of the spreader means, centrifugally spreading the material across the surface of the disk or bowl and dispersing the same from the edge thereof into an atmosphere cooler than the melting temperature to form the granulated product. For certain materials only a part of the powdery feed material is melted forming a liquid film carrying a major portion of substantially unaffected or minimally affected feed material to produce a product comprising individual granules containing a core as the major part of each granule with the original powdery material essentially unchanged maintained in self-sustaining form by a matrix of melted and resolidified particles bonded to each other at their surface.

Method for granulation

Solid particles or viscous liquid droplets of core material are encapsulated in a coating material largely as single particles with a single coherent coating, by feeding a suspension of the two materials onto a rotating surface. The suspension is centrifugally dispersed by the rotating surface into relatively large coated particles and relatively small droplets of coating material. Only the size of the droplets of unused coating corresponds to the droplets formed from atomization of the liquid coating material. The size of the coated particles depends on the size of the uncoated particles and is much less dependent upon the atomization characteristics of the rotating surface. Upon being thrown from the rotating surface, or falling from that surface, the droplets and coated particles are solidified by exposure to air and are separated by sieving, or the like. The solidified droplets of pure coating material may be recycled into the suspension. Coating of all particles is achieved by dispersing the individual components of core material in the coating material before the resulting suspension reaches the rotating surface.

Method for coating particles or liquid droplets

The pore size distribution of a microporous separation medium, such as a membrane or gel, is modified so as to provide it with a sharp upper cut-off of preselected molecular size. The modification is effected by first filling the pores of the separation medium with a volatile liquid, and then evaporating a controlled amount of the volatile liquid to form voids at the entrances to the pores. A concentrated solution of a cross-linkable or polymerizable pore-blocking agent, such as a protein, enzyme or polymeric material, is then applied to the surface of the separation medium. The pore-blocking agent is a material which is insoluble in the volatile liquid and whose molecular size distribution has a lower limit corresponding to the preselected molecular size, whereby the pore-blocking agent selectively enters only those pores larger than the preselected size and remains in the voids at the entrances to the pores. After removing excess pore-blocking agent solution from the surface of the separation medium, the pore-blocking agent is insolublized by cross-linking or polymerization so as to immobilize it within the voids and thereby obstruct the entrances to all of the pores larger than the preselected size.

Method for modifying the pore size distribution of a microporous

A set of block-like pillow components which can be assembled in various ways so to accomodate different body resting positions while sitting up, instead of laying down, the components also including one so to serve as a food tray, and in a modified design of the invention, the assembled units form a container for carrying food, the components being molded of plastic styrofoam.

Sleeping device for sitting position

Aluminum hydrogels which are stabilized at pH below 7 with a polymer containingcarboxyl groups, e.g., carboxy methyl cellulose or gum arabic. The gels are useful as phosphate binding agents in the treatment of hyperphosphatemia. Such polymers are incorporated during the formation of the aluminum hydrogel, permitting a high yield to be obtained, and preventing colloidal sol formation during exchange with monovalent anions.

Polyanion-stabilized aluminum hydrogels

A device for use by an artist in order to trace an actual scene or three dimensional object upon a transparent film or sheet; the device consisting of a frame having a pivotable easel leg so that the frame may stand upright, a transparent stiff plastic back sheet forming a window in the frame, a transparent thin plastic sheet or film unwound from a roll supported at one end of the frame so to be pulled across the window and retained in position between the back sheet and frame, an eye opening on the easel leg for observing the painting object from a constant point, and adjustable rulers attached to the frame for guiding the drawing of straight lines upon the film or sheet extending across the window.

Growing community of inventors

Kirkwood, MO, United States of America

Robert E Sparks