Greer Laboratories, Inc.

Robert E Esch

William P White, Jr

John A Richardson

The present invention comprises methods and compositions for immunotherapy. An aspect of the invention comprises administration of one or more allergens in compositions via oral and sublingual routes. Allergen compositions are administered in dosing intervals wherein the increase in the one or more allergens administered to the patient are provided in increasing volumes of a single concentration of at least one allergen.

Methods and compositions for dosing of allergens

There is provided a method for performing skin tests for biologic response which includes providing an applicator having at least one pick having at least one skin piercing epidermal point and being capable of carrying a load of testing substance such as biologic substances, such as an antigen, for skin testing for each pick, each of said sources being carried in a container having an opening. The applicator is placed in sealing relationship over each of the openings in the container to form a single unit of the combined applicator and source. The unit is then inverted so as to load each pick with an effective amount of substance to perform a skin test, reverting said unit, and the applicator is removed in loaded condition ready for use. The testing substances are epicutaneously deposited by piercing the patient's skin with each pick to a predetermined depth and observing the pierced skin for response to the testing substance.

Growing community of inventors

Lenior, NC, United States of America

Robert E Esch