Genetics Institute, Inc.

Ludwig Institute for Cancer Research Limited

Steven C. Clark

Agnes B. Ciarletta

Yu-chung Yang

Robert E. Donahue

Susan T. Ricciardi

Robert E Donahue

Steven C Clark

Yu-Chung Yang

Agnes B Ciarletta

Susan T Ricciardi

This invention provides a novel human erythropoietic growth factor and processes for producing it by recombinant DNA genetic engineering techniques.

DNA encoding the human cytokine, interleukin-9

The invention involves DNA molecules which encode a human protein of 144 amino acids, referred to as interleukin-9, or IL-9. The protein is an erythropoietic growth factor. Also disclosed are processes for producing the IL-9 protein via genetic engineering techniques.

Disclosed herein is the treatment of patients suffering from AIDS-type disease with erythropoietin alone or together with a colony stimulating factor, and/or an anti-viral agent and/or IL-2.

Methods of treating pancytopenia and AIDS by co-administering EPO and

An improved method for inducing leukocytosis in a primate is disclosed. The method includes co-administering IL-3 in conjunction with GM-CSF, such that the leukocyte count in the primate is synergistically raised.

Method of inducing leukocytosis with a combination of IL-3 and GM-CSF

Treatment of AIDS-type disease

Growing community of inventors

Shirley, MA, United States of America

Robert E Donahue