Dfine, Inc.

Norian Corporation

Robert D Poser

Andrew C Kohm

Kirti P Kamdar

Aaron Germain

Steve Kramer

Craig A Purdy

Nate Shirley

Csaba Truckai

Brent Richard Constantz

John H Shadduck

Gregory R McArthur

Christopher U Phan

Robert Luzzi

Mark T Fulmer

Dan Balbierz

Andy E Poursaid

Jimmy Chi-Yun Chan

Oleg Yurchak

Joshua Defosset

Eric Wong

The invention relates to a magnetic-navigation joint type puncture needle which comprises a head section and needle sections, wherein, the head section is made of stainless steel material with high magnetic conductivity and is connected with the following needle sections coaxially mounted with the head section through a flexible joint; two needle sections are also coaxially connected with each other through a flexible joint; the needle sections are made of non-magnetic stainless steel material; the flexible joints adopts serpentine tubes formed by melting and engraving cobalt-chromium alloy through laser; and both the head section and the needle sections can be bent, but the flexibility of the head section and that of the needle sections are smaller than the flexibility of the flexible joints. According to the invention, an extra magnetic field force is used to cause the head section of the needle to deflect, so that the following purposes can be achieved that the insertion direction of the needle can be changed, and the other needle sections also deflect with the deflection of the head section; accurate navigation for and control over puncture path and puncture position when the puncture needle performs a non-direct channel puncture in a human body; the puncture needle provided by the invention can reach niduses which other types of puncture needles can not reach; the application scope of minimally invasive surgery is expanded; iatrogenic injuries can be reduced; and patients can be benefited.

Ablation systems with parameter-based modulation and related devices and methods

The present disclosure relates to systems and methods for mixing and injecting fluid treatment, such as cement to treat bone or hard tissue. In some embodiments, a mixing apparatus may facilitate mixing within a syringe. Additionally, the syringe may be configured to extract bone cement from a cement mixer. A syringe for mixing and injecting cement may include a detachable handle that may be detached after extracting bone cement from a mixer to facilitate coupling to a high-pressure syringe for injection.

Cement mixing and injection system and methods

This invention relates to medical methods, instruments and systems for creating a controlled lesion using temperature to control the growth of the lesion. The treatment can be used in any tissue area and is particularly useful in or around a vertebral body. The features relating to the methods and devices described herein can be applied in any region of soft or hard tissue including bone or hard tissue.

Methods and systems for use in controlling tissue ablation volume by temperature monitoring

Devices and method discussed for device for delivering a pressurized substance to an opening in bone within a vertebral column, useful to provide access to structures in the vertebral so that a substance, such as bone cement can be delivered through a lumen or portal or for providing access to the opening in bone by a separate instrument.

Devices, methods and systems for affixing an access device to a vertebral body for the insertion of bone cement

Systems and methods for delivering bone cement into a bone can include a handle body defining a flow path, a thermal emitter in the handle body to apply energy to bone cement passing through the flow path, a source of bone cement and an injection cannula. The cannula can be in communication with the flow path such that inserting the cannula into a bone can allow a flow of bone cement therethrough to an opening at a distal end of the cannula. Other systems and methods for delivering bone cement into a bone can include an injector body with a handle portion, and a cannula, a bone cement container, a low pressure drive mechanism configured to effect a flow of bone cement from said container to the injector body and a high pressure drive mechanism configured to effect a flow of bone cement through the injector body into the bone.

Bone treatment systems and methods

A flowable, paste-like composition capable of setting in a clinically relevant period of time into an antimicrobial agent loaded apatitic product having sufficient compressive strength to serve as a cancellous bone structural material is provided. The subject compositions are prepared by combining dry ingredients with a physiologically acceptable lubricant and an antimicrobial agent, where the dry ingredients comprise at least two different calcium phosphates. The subject compositions find use in a variety of different applications, including orthopaedic, dental and cranio-maxillofacial applications.

Calcium phosphate cements comprising antimicrobial agents

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Scotts Valley, CA, United States of America

Robert D Poser