Ibis Biosciences, Inc.

Med-safe Systems, Inc.

Nse Products, Inc.

Qualigen, Inc.

Izi Corporation

Robert D Miller

Rex O Bare

Paul J Gleason

Jeffrey Christopher Smith

Steven A Hofstadler

Jared James Drader

Jose R Gutierrez

Kevin Oberkramer

Ronald K Bergold

Richard A Shillington

Jared H Nathanson

Dale G Kern

Vijay K Mahant

Christopher C Feistel

James C Hannis

Eva S Zinreich

Simion J Zinreich

Glenn D Walker

Kevin S Oberkramer

A device for delivery of TENS current, attachable to a handheld skin treatment device with a mechanical motion source, comprises a housing for mounting on the handheld skin treatment device, with a conductive skin contact head with first and second electrodes for receiving a TENS signal as a voltage established between the electrodes and a connector mounted in or on the housing and configured to interface with the mechanical motion source to receive the motion of the motion source. The device has an energy converter in the housing to convert the motion into electrical current, a power control circuit for receiving the electrical current and converting it into at least one power supply output voltage; and a signal generation circuit connected to the at least one the power supply output voltage for producing as an output a TENS signal for delivery to skin.

TENS attachment for device for cleansing and treating skin

The present invention provides systems and methods for analysis of samples, particularly biological and environmental sample to detect biomolecules of interest contained therein. A variety of system components are described herein, including, but not limited to, components for sample handling, mixing of materials, sample processing, transfer of materials, and analysis of materials. The invention further provides mechanisms for combining and integrating the different components and for housing, moving, and storing system components or the system as a whole. The systems may include any one or more or all of these components. The system finds particular use when employed for analysis of nucleic acid molecule using mass spectrometry, however, the invention is not limited such specific uses.

Systems for bioagent indentification

Systems, computer program products, and methods useful for handling or managing microplates are provided.

Microplate handling systems and related computer program products and methods

Sample processing units useful for mixing and purifying materials, such as fluidic materials are provided. A sample processing unit typically includes a container configured to contain a sample comprising magnetically responsive particles, and one or more magnets that are in substantially fixed positions relative to the container. A sample processing unit also generally includes a conveyance mechanism configured to convey the container to and from a position that is within magnetic communication with the magnet, e.g., such that magnetically responsive particles with captured analytes can be retained within the container when other materials are added to and/or removed from the container. Further, a sample processing unit also typically includes a rotational mechanism that is configured to rotate the container, e.g., to effect mixing of sample materials disposed within the container. Related carrier mechanisms, sample processing stations, systems, and methods are also provided.

Sample processing units, systems, and related methods

Cartridges useful for mixing materials, such as fluidic materials are provided. A cartridge typically includes a body structure having surfaces that define a cavity with upper and lower portions. A rotatable member generally extends along a horizontal axis in the upper portion of the cavity. One or more protrusions typically extend outward from the rotatable member and into the lower portion of the cavity, and are configured to mix the material when the material is disposed in the cavity. Related mixing stations, systems, kits, and methods are also provided.

Mixing cartridges, mixing stations, and related kits, systems, and methods

Methods and apparatus for automated sample analysis are provided in which a plurality actuators are involved in moving a samples from one compartment to another, and appropriate reactants are combined with the sample in one or more of the compartments. The actuators are preferably contained in a device that also has a detector, data reduction capabilities, and a printer. Contemplated signal detectors include a photomultiplier tube, a photodiode, and a charge-coupled device. Steps contemplated to be performed automatically include aliquoting the sample, diluting the sample, contacting at least a portion of the sample with a reagent having a substantially selective binding towards the analyte. Contemplated reactants include sense and antisense nucleic acids, antibodies and antigens, solid-phases such as paramagnetic beads, reagents, other substrates, and wash solutions.

Methods for conducting tests

A set of post-surgical gross pathology specimen marking devices which may be used to identify various surfaces of pathology specimens is presented. The device includes a set of pathology specimen markers which are releasably attached to a holder. The markers disclosed are of various shapes and designs, and each includes a gripper element. The markers are designed such that the gripper element may be manipulated to allow a portion of a pathology specimen to be pinched, pierced, or clipped by the gripper element thereby attaching the marker to the specimen. The markers are designed so they may be manipulated by using a tool (such as forceps) to attach the specimen marker to a pathology specimen in a matter of seconds.

Post-surgical gross pathology specimen marker

Disposable sharps container and mounting bracket

A combination of a secure disposable container and mounting bracket assembly therefor, comprises a generally box-like enclosed container having a top with a limited access closure for receiving medical sharps and for inhibiting access by a human hand, the container having a back wall with a downwardly extending latching slot at an upper edge thereof, and a latching tab at a lower edge thereof, a generally rectangular panel having a back mounting surface and mounting holes for mounting the panel to a vertical support surface, and mounting tabs for mounting the panel to another mounting bracket mounted on a vertical supporting surface, an upper edge for receiving the downwardly extending latching slot on the container, a lower transverse ledge, and lever operated can for camming the tab on the lower edge of the container into gripping engagement with the lower transverse ledge.

Combination disposable sharps container and mounting bracket

Growing community of inventors

Costa Mesa, CA, United States of America

Robert D Miller