Medtronic Ave, Inc.

Other

Abbott Cardiovascular Systems, Inc.

Arterial Vascular Engineering Inc.

Medtronic Vascular, Inc.

Robert D Lashinski

Matthew J Birdsall

Dennis L Brooks

Philip Jon Haarstad

Bradley A Jendersee

Nasser Rafiee

James Clayton Peacock, Iii

Nareak Douk

Howard J Leonhardt

Jerry Brightbill

David S Brin

Michael D Boneau

Vance E Swanson

Antonio Colombo

Michael Scott Williams

Albert Harold Dunfee

Michael S Noone

Bruce Adams

Michael D Bonneau

John E Nolting

Steven Dapolito

Samuel L Shull

Barbara DeVaux

Geoffrey A Orth

Timothy P Collins

Heng Mao

Ahmed Malek

Bradly A Jendersee

Brad Jendersee

A catheter-based deployment system for deploying cellular material () into the heart muscle (). The deployment system includes a guiding catheter () and a needle assembly () capable of sliding within the guiding catheter. The needle assembly () terminates in a tip () having at least one side with an opening () in communication with a lumen () disposed within the needle assembly (). Once the guiding catheter () is positioned, the needle assembly () is advanced until the tip () penetrates the muscle wall (). At a predetermined depth the cellular material () may be deployed into the muscle wall () via a push rod () disposed through the lumen of the needle assembly ().

Deployment system for myocardial cellular material

A catheter-based deployment system for deploying cellular material () into the heart muscle (). The deployment system includes a guiding catheter () and a needle assembly () capable of sliding within the guiding catheter. The needle assembly () terminates in a tip () having at least one side with an opening () in communication with a lumen () disposed within the needle assembly (). Once the guiding catheter () is positioned the needle assembly () is advanced until the tip () penetrates the muscle wall (). At a predetermined depth the cellular material () may be deployed into the muscle wall () via a push rod () disposed through the lumen of the needle assembly ().

An endolumenal medical device assembly is provided for use in a bifurcation region of a body lumen. An expandable prosthesis, preferably an endolumenal support device such as a stent, is included in the assembly and is adjustable from a radially collapsed condition to a radially expanded condition. The expandable prosthesis further includes a prosthesis passageway and a side port through which the prosthesis passageway communicates externally of the prosthesis. A dilator or an access device is engaged within the prosthesis passageway and also through the side port while the expandable prosthesis is in the radially collapsed condition. By coupling a guidewire to an access device engaged within the side port and positioning the guidewire therein, the expandable prosthesis may be positioned in the bifurcation region such that its distal end portion is in a first branch lumen extending from the bifurcation, its proximal end portion is in a common proximal lumen of the bifurcation region, and the side port is aligned with an entrance zone to a second branch lumen extending from the bifurcation. When the expandable prosthesis is positioned at the bifurcation region in this orientation, the access device maintains percutaneous translumenal access to the second branch lumen through the prosthesis passageway and the side port while the expandable prosthesis is adjusted from the radially collapsed condition to the radially expanded condition. In addition, a dilator when engaged within the side port is adapted to expand the bore formed by the side port from an initial inner diameter to a larger expanded inner diameter. A second, lateral expandable prosthesis can also be coupled to the first expandable prosthesis at a location adjacent to the side port such that the dilator or access device extending through the side port is engaged within a lateral prosthesis lumen, extending through the lateral expandable prosthesis.

Endolumenal prothesis and method of use in bifurcation regions of body lumens

An endolumenal prosthesis delivery assembly includes an endolumenal prosthesis which is delivered to a desired location within a body lumen by used of first and second delivery members. The first delivery member has a prosthesis coupler that is adapted to removeably engage the prosthesis during delivery to the desired location and to release the prosthesis and implant it at the desired location. The second delivery member has an anchor on its distal end portion which is adapted to secure the second delivery member within the body lumen distally of the desired location for stenting. Once the second delivery member is anchored, the first delivery member is slideably advanced over the second delivery member until the prosthesis is positioned at the desired location. The anchor along the second delivery member according to this assembly is either an expandable member, such as a balloon, or is otherwise adapted to engage the body lumen wall, such as by use of suction or other mechanical means. An expansion member on the first delivery member, such as provided at the prosthesis coupler, expands the prosthesis to engage the body lumen wall.

Endolumenal prosthesis delivery assembly and method of use

The present invention is a distal protection device for use during a vascular treatment, such as angioplasty or atherectomy. A filter assembly located on the distal end of a delivery member is deployed distally of the vascular region to be treated to capture emboli released during and immediately after the procedure. The filter is then retracted to retain any captured emboli and then removed from the patient.

Distal protection device

The present invention is a collapsible blood filter for use during a vascular procedure, such as angioplasty or stent deployment. A filter made of braided filaments is located on the distal end of a delivery member, and the filter is deployed downstream of the vascular treatment site to capture emboli released during and immediately after the procedure. Optimal braid geometry of the filter ensures that captured emboli will be retained during collapse and removal of the filter following the procedure.

Collapsible blood filter with optimal braid geometry

A delivery, deployment and retrieval device for a stent made from a phase-change material includes a balloon catheter modified to allow the stent to be secured on the outside of the balloon without the need for a sheath. A temperature-controlled fluid to effect a phase change to expand the stent is injected through an inflation lumen to maintain the selected temperature and to inflate the balloon. The balloon maintains intimate physical and thermal contact with the stent during deployment. One or more exit apertures are provided for the fluid to escape from the inflation lumen and enhance the phase change by bathing the stent with the fluid.

Method and apparatus for delivery deployment and retrieval of a stent comprising shape-memory material

An endolumenal medical device assembly is provided for use in a bifurcation region of a body lumen. An expandable prosthesis, such as a stent, is included in the assembly and is adjustable from a radially collapsed condition to a radially expanded condition. The expandable prosthesis includes a prosthesis passageway and a side port. A dilator or an access device is engaged within the prosthesis passageway and also through the side port while the expandable prosthesis is in the radially collapsed condition. The expandable prosthesis may be positioned in the bifurcation region such that its distal end portion is in a first branch lumen extending from the bifurcation, its proximal end portion is in a common proximal lumen of the bifurcation region, and the side port is aligned with an entrance zone to a second branch lumen extending from the bifurcation. When the expandable prosthesis is so positioned the access device maintains percutaneous translumenal access to the second branch lumen through the prosthesis passageway and the side port while the expandable prosthesis is adjusted from the radially collapsed condition to the radially expanded condition. A dilator may also to expand the bore formed by the side port from an initial inner diameter to a larger expanded inner diameter. A second, lateral expandable prosthesis can also be coupled to the first expandable prosthesis at a location adjacent to the side port and engaged by the dilator or access device extending through the side port.

Endolumenal prosthesis and method of use in bifurcation regions of body lumens

A stent-graft assembly having a thin-walled membrane and method of preparing the same are disclosed. In a first embodiment, the assembly comprises a stent, a coating and a porous membrane, wherein the membrane is less than 0.040 inch thick or less. Portions of the coating extend into the pores of the thin membrane to sealingly engage the membrane to achieve secure adhesion. In a second embodiment the coating and thin membrane bond to form a homogenous structure. In an alternative embodiment, the assembly comprises an inner and outer thin membrane bound to one another through the interstices of the support member and a coating at the proximal and distal regions. In any of the foregoing embodiments, the proximal and distal regions of the stent-graft assembly may comprise an additional coating, whereby layers of material are sealed, thereby minimizing thrombogenic potential of free ends of the assembly.

Stent-graft assembly with thin-walled graft component and method of manufacture

The present invention is a distal protection device for use with a delivery member. A filter assembly is located on the distal end of the delivery member. The filter is deployed distally of the region to be treated to capture emboli released during and immediately after the procedure. The filter is then retracted to retain any captured emboli and then removed from the patient.

An endoprosthesis is provided having an expandable, generally cylindrical body portion defining an inside surface and an outside surface. The inside surface is preferably regular and smooth to yield a low coefficient of friction, while the outside surface is modified to yield a relatively high coefficient of friction with a vessel surface, includes a macroscopic surface modification to engage the vessel surface, or includes an adhesive coating that bonds the stent to the vessel surface.

Method and apparatus to prevent stent migration

A encapsulated stent device for implantation within the vascular system includes a balloon of a balloon catheter formed around and adhered to a wire-like stent so that the outer surface of the device is more regular for delivery through the vascular system without an exterior sheath. The encapsulation securely anchors the stent to the balloon and maintains a low profile for negotiation of tortuous and narrowed vessels. Encapsulation requires placement of the stent over the balloon, placement of a sheath over the stent on the balloon, heating and preferably pressurization of the balloon to cause it to expand around the stent within the sheath, and cooling while preferably maintaining pressure to cause the balloon to adhere to the stent and to set the shape of the expanded balloon. Retainers may be placed at the distal and/or proximal ends of the stent during the encapsulation process, or the balloon material may expand to form retainers. The balloon defines at least three folded wings for symmetrical expansion of the stent, and one or more connected or non-connected stents may be encapsulated depending upon the area to be treated.

Stent delivery and deployment method

A stent for helping to hold open a lumen in a tubular body structure has at least one axial portion (preferably an axial end portion) that stents the surrounding portion of the tubular body structure to a lesser degree than another axial portion of the stent. For example, the stent portion that stents to a lesser degree may be circumferentially weaker than the other stent portion, or it may recoil more than the other stent portion after the stent is applied by being circumferentially expanded and then released.

Growing community of inventors

Sebastopol, CA, United States of America

Robert D Lashinski