Optiscan Biomedical Corporation

Robert D Gaffney

James Roswell Braig

Daniel S Goldberger

Bernhard B Sterling

Philip C Hartstein

Peter Rule

Julian M Cortella

Mark D Agostino

Martin J Fennell

Jennifer H Gable

Kenneth I Li

Peng Zheng

Kenneth G Witte

W Dale Hall

Heidi M Smith

Ken Li

Ken G Witte

Mike A Munrow

David C Klonoff

David Klonoff

Jane J Sheill

A method determines an analyte concentration in a sample. The sample includes the analyte and a substance. The method includes providing absorption data of the sample. The method further includes providing reference absorption data of the substance. The method further includes calculating a substance contribution of the absorption data. The method further includes subtracting the substance contribution from the absorption data, thereby providing corrected absorption data substantially free of a contribution from the substance.

Method of determining analyte concentration in a sample using infrared transmission data

A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.

Reagent-less whole-blood glucose meter

A method uses spectroscopy to determine an analyte concentration in a sample. The method includes producing an absorbance spectrum of the sample. The method further includes shifting the absorbance spectrum to zero in a wavelength region. The method further includes subtracting a water or other substance contribution from the absorbance spectrum.

Pathlength-independent methods for optically determining material composition

A method determines an analyte concentration in a sample including the analyte and a substance. The method includes providing an absorption spectrum of the sample. The absorption spectrum has an absorption baseline. The method further includes shifting the absorption spectrum so that the absorption baseline approximately equals a selected absorption value in a selected absorption wavelength range. The method further includes subtracting a substance contribution from the absorption spectrum. Thus, the method provides a corrected absorption spectrum substantially free of a contribution from the substance.

Method of determining an analyte concentration in a sample from an absorption spectrum

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Atherton, CA, United States of America

Robert D Gaffney