The General Hospital Corporation

Robert Carruth

Guillermo J Tearney

Michalina Gora

Brett Eugene Bouma

Tao Wu

Kengyeh Ken Chu

Norman S Nishioka

Chulho Daryl Hyun

Kevin Gallagher

Moon Gu Lee

Nima Tabatabaei

Jenny Sauk

Weina Lu

Milen Stefanov Shishkov

Dongkyun Kang

Timothy Nehiley Ford

Timothy N Ford

Dongyun Kang

Exemplary apparatus and method can be provided. For example, using at least one light source first arrangement, it is possible to provide pulses of light to at least one portion of a biological structure. At least one detector second arrangement can be used to detect images from the portion(s) based on the pulses, and provide data based on the detection. With at least one configuration, it is possible prevent and/or reduce a movement of the apparatus within at least one anatomical body (i) is a particular surface of the apparatus, (ii) covers at least one portion of the surface, and/or (iii) extends from the surface. In addition or alternatively, with at least one computer third arrangement, it is possible to receive the data, and control a timing of at least one of activation or deactivation of at least one portion of the first arrangement based on the data.

Method and apparatus for recording microscopic images from within a living organism using an implantable device

Method and apparatus for recording microscopic images from within a living person or organism using an implantable device

An exemplary apparatus for obtaining data for at least one portion within at least one luminal or hollow sample can be provided. For example, the apparatus can include a first optical arrangement configured to transceive at least one electromagnetic radiation to and from the portion(s). The apparatus can also include a wavelength dispersive second arrangement, which can be configured to disperse the electromagnetic radiation(s). A housing can be provided with a shape of a pill, and enclosing the first and second arrangements.

Apparatus, device and method for capsule microscopy

According to exemplary embodiments of the present disclosure, apparatus, device and method can be provided which can provide imaging of biological tissues, e.g., luminal organs in vivo, using optical techniques in an automatic or semiautomatic manner. The exemplary apparatus, device and method can utilize a tethered capsule catheter with a mechanism for manual, semi-automatic or automatic traversing in the luminal organ with a controlled velocity and/or image quality. The exemplary apparatus can include feedback information about tension applied to the catheter during its movement that can be used to adjust velocity and assure patient comfort and safety for example during passing through natural sphincters and/or narrowing of the luminal organs and preventing from breaking of the catheter. The exemplary apparatus can also adjust velocity in order to provide good quality of acquired images, for example to engaged peristalsis and provide contact with the tissue. In one exemplary embodiment of the present disclosure, the exemplary mechanism for a controlled advancement of the catheter can be positioned outside of the patient's mouth, and can include a position sensor providing information about the position of the capsule in respect to the luminal organ for orientation of the acquired data.

System and method for facilitating manual and/or automatic volumetric imaging with real-time tension or force feedback using a tethered imaging device

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Arlington, MA, United States of America

Robert Carruth