International Minerals & Chemical Corp.

Robert C McCrae

Emil P Lira

Walter M Barker

Novel 6-amino-9-(substituted benzyl)purines are prepared by allowing an appropriate substituted benzyl halide, e.g., a substituted benzyl chloride, to react with adenine under the appropriate conditions. Oxidation of the resulting purine derivatives yields the corresponding N.sup.1 -oxides. These compounds, i.e., both the purine derivatives and the N.sup.1 -oxides thereof, have anti-coccidial activity and are useful for controlling cecal and/or intestinal coccidiosis when administered in minor quantities to animals, in particular to poultry, usually in admixture with animal sustenance.

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Lake Zurich, IL, United States of America

Robert C McCrae