P B Diagnostic Systems, Inc.

Behring Diagnostics Gmbh

Robert C MacIndoe, Jr

Ernest W Long

Fareed Kureshy

Dina Frenkel

Melvin S Henriksen

Charles A DeAngelis

An automated analytical instrument for conducting assays for components of interest in fluid samples. The instrument includes a rotably mounted supply unit or segment adapted to hold a plurality of foil-sealed magazines containing assay modules, a testing system for assaying a fluid sample for a component of interest using an assay module, an assay module transport assembly for transporting an assay module from a magazine in the supply unit to the testing system, and a microprocessor for controlling the operation of the automated analytical instrument. In one embodiment, the assay module transport assembly includes a cutter assembly for cutting away a layer of material such as a thin foil layer covering a desired assay module within the magazine, an assay module receiving platform disposed in front of the magazine, an assay module ejector mechanism for pushing an assay module from the magazine onto the assay module receiving platform, and an assay module transfer mechanism for moving the assay module from the assay module receiving platform to the testing system. The cutter assembly and the assay module receiving platform are movable vertically on a first elevator assembly, and the assay module ejector assembly is movable vertically on a second elevator assembly.

Cutting apparatus for use in an automated analytical instrument

Assay module transport apparatus for use in an automated analytical

Assay module magazine

An automated assay system includes a temperature controlled chamber with a conveyor therein. The conveyor carries berths past a port in a sidewall of the chamber to permit insertion and extraction of assay cartridges via the port into respective ones of the berths. An injector disposed outside the chamber and at the port includes a loader arm for advancing cartridges along a path through the port to accomplish insertion and extraction of a cartridge. A track is provided in the injector for guiding the assay module. A portion of the track connects by a swing arm to a pivot allowing the track portion to be swung away from the path for ejection of a cartridge. A door which provides for opening and closing of the port is connected to the swing arm to move concurrently with the swinging of the track portion. This allows for automatic closure of the port subsequent to an insertion or an extraction of a cartridge, and automatic opening of the port prior to insertion or extraction of the cartridge.

Incubator port closure for automated assay system

Growing community of inventors

Linwood, MA, United States of America

Robert C MacIndoe, Jr