E.i. Dupont De Nemours and Company

Robert C DiLuccio

Bruce J Aungst

Opioid-containing pharmaceutical compositions are provided which are useful in effecting transdermal delivery of a therapeutic dose of the opioid to the systemic circulation of a mammal. These pharmaceutical compositions consist essentially of the opioid, a penetration enhancer which is at least one of a saturated fatty alcohol or fatty acid of 8-15 carbon atoms or of an unsaturated fatty alcohol or fatty acid of 8-18 carbon atoms, and a suitable pharmaceutical carrier, preferably propylene glycol.

Trandermal delivery of opioids

A laminate of a first layer of a lamellar heterogeneous blend of a polyolefin and a condensation polymer incompatible with the polyolefin, and a second layer of a polyolefin, said layers being melt bonded together.

Growing community of inventors

Wilmington, DE, United States of America

Robert C DiLuccio