Rodan & Fields, LLC

Robert Bianchini

Christine Marie Crane

Olga Dueva-Koganov

George Paul Majewski

Taylor Oswald

Kathy Ann Fields

Timothy John Falla

Kathryn Pregerson Rodan

Dzung Q Le

John Simon Craw

Gabriele Di Fiore

Angela M Rivera

The compositions of various embodiments include a tocopherol phosphate mixture (TPM) comprising a liposome having a lipid bilayer and an internal aqueous compartment, a lipophilic ingredient, a polar solvent system, an alcohol, a base, and a water soluble phase, wherein the liposome is made of a tocopherol phosphate derivative, wherein the lipophilic ingredients are entrapped in the lipophilic bilayer of the liposome, and wherein a water soluble ingredient is dissolved in the water soluble phase and is in the internal compartment of the liposome. The methods include improving the look of skin particularly of the neck and décolletage, increasing expression of an extracellular matrix proteins in skin, improving a keloid scar in a subject, and improving aging skin. Additionally, methods for preparing the compositions are described herein.

Cosmetic compositions

The antioxidant compositions of various embodiments comprise methyl carboxymethylphenylaminocarboxy propylphosphonate, also known as MCAP, (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid, also known as rosmarinic acid, and 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[&#x3b1;-L-rhamnopyranosyl-(1&#x2192;6)-&#x3b2;-D-glucopyranosyloxy]-4H-chromen-4-one, also known as rutin wherein the antioxidant composition demonstrate a synergistic effect compared with the MCAP, the rosmarinic acid, or the rutin alone. The methods include treating skin or hair damaged by reactive oxygen species, preventing skin or hair damage, and treating aged skin.

Synergistic antioxidant compositions

This disclosure is directed to compositions comprised of retinaldehyde, one or more skin conditioning agents, and, optionally, one or more additional retinoids. This disclosure is directed. Embodiments are also directed to compositions comprised of retinaldehyde, one or more peptides, one or more skin conditioning agents, one or more calcium containing agents, and, optionally, one or more additional retinoids. Embodiments are also directed to compositions comprised of retinaldehyde, one or more peptides, one or more skin conditioning agents, one or more calcium containing agents, and, optionally, one or more additional retinoids. Additional embodiments disclose methods for treating the skin wherein a characteristic of the skin is improved, the characteristics include firmness, elasticity, fine lines and wrinkles, skin texture, dullness, dyschromia, skin tone, reduction or elimination of acne, and any combination thereof. This disclosure is also directed to kits used for treating the skin with the compositions described herein.

Retinaldehyde containing compositions and methods of use

Growing community of inventors

Dana Point, CA, United States of America

Robert Bianchini