Board of Trustees of the University of Arkansas

Okayama University

Nowdiagnostics, Inc.

Robert Beitle

Ingrid Fritsch

Zoraida Aguilar

Joshua Sakon

Osamu Matsushita

Kevin Clark

Suresh Kumar Thallapuranam

David S McNabb

Andrew Proctor

H Michael Cheung

Christa Noel Hestekin

Latha Devareddy

Reddy Yettella Yenkata Ramesh

Noel Romey

Steven Setzer

Bryce Cameron Jones

Kimberly Cribbs

Allysa Swearingen

Stephanie Beitle

Hazim Aljewari

Brandon Hart

Rudra Palash Mukherjee

Ahmed Elmasheiti

Michael Rienisch

Vicki Thompson

The present invention provides collagen-binding agents that can be used to treat wounds, ischemic heart disease, and other conditions. The collagen-binding agents comprise a therapeutic agent, a protease cleavage site, and a collagen-binding domain. The present invention further provides pharmaceutical compositions and biomedical devices comprising the disclosed collagen-binding agents, as well as methods for treating a condition using the collagen-binding agents.

Release of growth factors at wound healing stages

The present invention provides a device and method for testing a material for the presence of DNA. The system includes a centrifuge, a microchip performing cell lysis and an enclosure that contains an isothermal ballast material and chromogenic agent that melts at a specific temperature and displays a color change, respectively.

Simple LAMP PCR design for low resource setting and minimal environmental footprint

Photoluminescent proteins resistant to protein cleavage reagents are described herein. In being resistant to cleavage reagents, such photoluminesncent proteins can reduce the number of digestion or cleavage products, thereby simplifying quantification and purification of recombinant protein compositions. In some embodiments, a photoluminescent protein described herein comprises an amino acid sequence having an absence of internal methionine residues.

Cleavage resistant photoluminescent proteins and applications thereof

This invention relates generally to trans-,trans-conjugated linoleic acid compositions and use thereof, and in particular to trans-,trans-conjugated linoleic acid produced from photoisomerization of soy oil in the presence of an antioxidant, and used in pharmaceutical, nutraceutical and human and animal food compositions for improved health. The invention also relates generally to a method for treatment and prevention of health-related disorders of obesity by administration of pharmaceutical, nutraceutical and/or food compositions containing and/or prepared from trans-,trans-conjugated linoleic acid-rich soy oil.

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A user interface for software applications enables the full use of graphical user interface (GUI) software, particularly engineering design software, by visually impaired individuals. The interface combines tactile representations of graphical elements, non-visual cues, and a hardware element to allow the effective placement and interconnection of graphic elements using design software.

User interface for software applications

Methods and devices for improved chemical and biological detection assays combined well defined microstructures having independently addressable electrodes with various surface immobilization electrochemical assays. Combining known chemical detection immobilization assays, electrochemically active moieties with microstructures having independently addressable electrodes provides for vastly improved methods of detecting microorganisms, chemical compounds, and measuring membrane transport.

Self-contained microelectrochemical bioassay platforms and methods

A novel, surface immobilization electrochemical assay allows for rapid, accurate and highly sensitive detection of microorganisms and biological molecules. Known surface immobilization methods are utilized to bind an analyte to a surface. A binding material with a covalently attached electroactive complex generates electrical current in the presence of analyte. An electrode is used to detect the current, that is directly related to the concentration of analyte. The invention is especially suitable for detection of

Electrochemical method for detecting water born pathogens

Methods and devices for improved chemical and biomass detection assays combined well defined microstructures having independently addressable electrodes with various surface immobilization electrochemical assays. Combining known chemical detection immobilization assays, electrochemically active moieties with microstructures having independently addressable electrodes provides for vastly improved methods of detecting microorganisms, chemical compounds, and measuring membrane transport.

Growing community of inventors

Fayetteville, AR, United States of America

Robert Beitle