Other

Diabcell Pty Ltd

Auckland Uniservices Limited

The University of Auckland

Fac8cell Pty Limited

Neurotrophincell Pty, Limited

Living Cell Products Pty Ltd.

Diabell Pty Ltd.

Robert Bartlett Elliott

Riccardo Calafiore

Gusseppe Basta

Jeremy P Hill

Olga Garkavenko

Christopher D Thanos

Alfred V Vasconcellos

Alexander B Ferguson

Dwaine Emerich

Livia Del Carmen Escobar Orellana

Chris Thanos

Brian W Edgar

Stephen John Martin Skinner

The invention relates to an improved method of culturing hepatocyte cells and non-hepatocyte cells that are capable of secreting liver secretory factors and their use in implantable compositions for treating liver diseases and disorders in patients in need thereof.

Culture and use of cells that secrete liver secretory factors

The invention relates to developments in the treatment of diabetes in mammals. Particularly it relates to a method of preparing a xenotransplantable porcine islet preparation capable upon xenotransplantation of producing porcine insulin in an appropriate recipient mammal, the method including or comprising the steps of: Further, the invention relates to a method of encapsulation of a xenotransplantable porcine islet preparation, and transplantation of such a preparation, or a capsule containing such a preparation, into an appropriate recipient mammal.

Preparation and xenotransplantation of porcine islets

The present invention is directed to the use of choroid plexus cells and/or choroid plexus conditioned media for enhancing the growth, survival and/or maintenance of function of non-choroid plexus cells grown in long term or short term culture.

Choroid plexus preparation and uses thereof

The invention relates to methods of selecting and maintaining a population of pigs having a low copy number of porcine endogenous retrovirus, and the use of such pigs as a source of cells, tissue and/or organs suitable for xenotransplantation. The invention further relates to methods for selecting cells, tissue and/or organs from such pigs for suitability for use in xenotransplantation.

Swine population having low levels of porcine endogenous retrovirus and uses thereof

The invention is based on the discovery that certain variants of &#x3b2;-casein may induce Type-1 diabetes in susceptible individuals while other variants do not. The invention consists of the selection of non-diabetogenic milk producing cows and recovering and processing their milk and milk products. Another aspect of the invention is selectively breeding cows which produce the non-diabetogenic milk.

Method of selecting non-diabetogenic milk or milk products and milk or milk products so selected

The invention is based on the discovery that certain variants of &bgr;-casein may induce Type-1 diabetes in susceptible individuals while other variants do not. The invention consists of the selection of non-diabetogenic milk producing cows and recovering and processing their milk and milk products. Another aspect of the invention is selectively breeding cows which produce the non-diabetogenic milk.

Method for reducing the risk of developing diabetes

A method and apparatus for dispensing inhalable material includes the steps of indicating to a patient that a breath should be taken, detecting the start of inhalation, causing inhalable material to be supplied to the air passages of the patient during a preselected part of the period of inhalation, then after a predetermined inhalation period substantially preventing further inhalation, indicating to the patient that exhalation should begin, detecting the start of exhalation, and after a predetermined exhalation period again indicating that a breath should be taken. The dispenser includes a supply of inhalable material, a mouthpiece, and a control device for selectively controlling the flow between the supply and the mouthpiece, as well as between the supply and the atmosphere. The device also includes a signalling means for indicating to the user when to inhale and subsequently when to exhale. Also included is a detection device to detect commencement of inhalation and to start a timer, as well as a second detection device to detect commencement of exhalation and to cause a second timer to start, to time a predetermined exhalation period.

Method of dispensing and/or a dispenser

Growing community of inventors

Auckland, New Zealand

Robert Bartlett Elliott