The University of Texas System

Research Development Foundation

Profectus Biosciences, Inc.

Robert B Tesh

Scott C Weaver

Farooq Nasar

Rodion V Gorchakov

Alan D T Barrett

Hilda Guzman

Walter Ian Lipkin

Gustavo Palacios

Theresa E Latham

Mohammad F Saeed

John H Eldridge

David K Clarke

David W C Beasley

Stefan Hamm

Robert E Shope

Heiman Wang

C Todd Davis

Rebecca Nowak

Naomi Forrester

Demetrius Matassov

Robert L Seymour

Andrew D Haddow

Certain embodiments are directed to recombinantencoding a heterologous polynucleotide and methods of using the same.

Recombinant isfahan viral vectors

Embodiments are directed compositions related to Eilat virus and uses thereof.

Alphavirus compositions and methods of use

Certain embodiments are directed to Negevirus and their polynucleotides and polypeptides.

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The present invention concerns isolated attenuated flaviviruses , such as West Nile viruses, having modifications that provide phenotypic varation, particularly in comparison to a more virulent reference strains. The invention encompasses the isolated viruses and immunogenic compositions thereof, in addition to methods to produce and utilize same.

Flavivirus variants having phenotypic variation and immunogenic compositions thereof

The present invention provides DNA encoding an Oropouche NP protein selected from the group consisting of: (a) isolated DNA which encodes an Oropouche NP protein; (b) isolated DNA which hybridizes to isolated DNA of (a) above and which encodes an Oropouche NP protein; and (c) isolated DNA differing from the isolated DNAs of (a) and (b) above in codon sequence due to the degeneracy of the genetic code, and which encodes an Oropouche NP protein. Also provided is a kit for the immunodetection of Oropouche virus.

Nucleotide sequence of the nucleocapsid gene of oropouche virus

Growing community of inventors

Galveston, TX, United States of America

Robert B Tesh