Bayer Corporation

Ciba Corning Diagnostics Corp.

Chiron Diagnostics Corporation

Other

Robert B Green

Kevin J Sullivan

Steven C Lepke

Dennis R Conlon

James E Flaherty

Richard W Mason

Minna A Rannikko

Peter G Edelman

Paul A D'Orazio

Robert R McCaffrey

Thomas C Maley

Mark W Boden

Bonnie C Dalzell

John A Zalenski

James E Rasmussen

Richard L Schulkind

Norman K Parker

Multi-analyte reference solutions having a stable partial pressure of oxygen (pO ) in zero headspace packaging and methods for preparing such solutions are disclosed. The solutions have long shelf and use lives when stored at room temperature and are packaged in laminated foil containers having low or no oxygen reactivity. Access devices are also disclosed.

Multi-analyte reference solutions with stable pO2 in zero headspace containers

Sensor package

Multi-analyte reference solutions having a stable partial pressure of oxygen (pO.sub.2) in zero headspace packaging and methods for preparing such solutions are disclosed. The solutions have long shelf and use lives when stored at room temperature and are packaged in laminated foil containers having low or no oxygen reactivity. Access devices are also disclosed.

Multi-analyte reference solutions with stable pO.sub.2 in zero headspace

A novel flexible package for an oxygen reference solution has been developed. This package is made from a laminated film including preferably polypropylene as the inner layer, aluminum foil as the middle layer, and polyester as the outer layer. The seams are heat sealed, while an optional access device for allowing access to the solution after the storage period, is attached to the inside wall of the bag without breeching the middle barrier layer.

Method of packaging oxygen reference solution using flexile package with

The invention features a sample probe and reagent selector valve that enables selection among multiple functions of withdrawing a biological sample from a syringe or capillary into a fluid parameter sensor module, providing calibration and quality control reagents to the sensor module, and flowing a washing fluid through intake passages to prevent cross-contamination and clogging. The valve and sensor module are used in conjunction with an automated analytical instrument, such as an automated blood analyzer, to increase the speed of the analysis, minimize cross contamination between samples, and to overcome the inherent dangers of using the conventional needle/syringe or capillary methods of withdrawing fluids to be tested. The design of the valve provides performance benefits in the form of lower sample and reagent waste volumes, elimination of auxiliary valves and manifolds, and superior performance and reduced cost.

Multifunction valve

A solid state, multi-use electrochemical sensor having an electrically nonconductive substrate, a working electrode, and a semi-permeable membrane covering the working electrode. The working electrode includes an electrically conductive material adhered to a portion of the substrate. A first portion of the conductive material is covered with an electrically insulating dielectric coating, and a second portion of the conductive material is covered with an active layer. The active layer includes a catalytically active quantity of an enzyme carried by platinized carbon powder particles, which are distributed throughout the active layer. A sensor package for incorporating a sensor is provided.

Electrical contact

Sample chamber

Electrochemical sensor package

Metal melted and poured into molds, mounted on a conveyor, at a first station. Metal cools to rolling temperature during conveyance to second station where hydraulic ram ejects ingots from molds. Ingots are immediately fed to rolling mill. Molds have interior refractory linings. Embedded in linings are electrical resistance heating elements that heat exterior side surfaces of ingots, between first and second stations, to prevent those surfaces from reducing below rolling temperatures while interior temperatures of ingots reduce to levels suitable for rolling.

Method and means for producing rolled metal products

Growing community of inventors

Hopkinton, MA, United States of America

Robert B Green